THE FREQUENCY AND THE CHARACTER OF LESIONSIN THE VISUAL PATHWAY OF THE PATIENTS PRESENTING WITH VIRAL ENCEPHALITES


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The results of the evaluation of the state of the visual pathway in the patients presenting with viral encephalites are presented. The study included 30 children at the age ranging from 5 to 12 years in whom visual evoked potentials (VEP) were investigated within 2 weeks after the appearance of the first signs of the disease. Latency and amplitude of the P100 peak were compared between the patients with varicella and tick-borne encephalitis. It was shown that the conductivity along the visual pathway was disordered (slowed down) in 30% of the patients (P100 latency lenthening) while the functional activity of neurons of the visual cortex was impaired in 40% of them (P100 amplitude lowering). Severely disturbed conductivity of the visual pathway was documented in 3% of the patients. The comparison of visual evoked potentials in the children presenting with varicella and tick-borne encephalitis failed to reveal a significant difference. The results of the present work suggest considerable resistance to the development of anatomical lesions in the visual pathway and enhanced functional susceptibility of neurons of the visual cortex to the general state of the central nervous system in the children presenting with various clinical forms of viral encephalitis.

作者简介

Vladislav Voitenkov

Federal state budgetary institution «Research Institute of Children’s Infections», Russian Federal Medico- Biological Agency

197022, Санкт-Петербург, ул. проф. Попова, 9

Vladimir Komantsev

Federal state budgetary institution «Research Institute of Children’s Infections», Russian Federal Medico- Biological Agency

197022, Sankt-Peterburg, Russian Federation

Natalia Skripchenko

Federal state budgetary institution «Research Institute of Children’s Infections», Russian Federal Medico- Biological Agency

197022, Sankt-Peterburg, Russian Federation

Marina Savina

Federal state budgetary institution «Research Institute of Children’s Infections», Russian Federal Medico- Biological Agency

197022, Sankt-Peterburg, Russian Federation

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