An investigation of the dissolution of acetylsalicylic acid in supercritical carbon dioxide

Аннотация

The dissolution of acetylsalicylic acid in supercritical carbon dioxide (SC–CO₂) is investigated using Fourier transform IR spectroscopy. Temporal dependences of integrated intensities of the absorption band of acetylsalicylic acid (ASA) near 1199 cm^–1 are measured for various ASA charges placed into a cuvette. Molar fractions of ASA in the saturated solution in SC–CO₂ are determined at a temperature of 40°C and pressures of 10.0 and 15.0 MPa, and the components are 2.10 ± 0.25 × 10^–4 and 11.0 ± 1.5 × 10^–4, respectively.