Kinetic Isotope Effect in the Oxidation Reaction of Linoleic Acid Esters in Micelles

Resumo

In the oxidation of linoleic acid esters in micelles the high kinetic isotope effect has been found to be equal to 23.6. The low value of the oxidation rate of linoleic acid ester deuterated in bis-allylic position (LD₂) is explained by the absence of its interaction with HO₂^. radicals formed in the course of oxidation. The influence of superoxide dismutase on kinetics of (LD₂) oxidation inhibited and non-inhibited by nitroxyl radical, as well the absence of LD₂ oxidation when the process is initiated by HO₂^. radicals, confirms this conclusion.