Cancer stem cell molecular markers verified in vivo
- Авторлар: Kim Y.S.1, Kaidina A.M.1, Chiang J.2, Yarygin K.N.1, Lupatov A.Y.1
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Мекемелер:
- Institute of Biomedical Chemistry
- National Cheng Kung University
- Шығарылым: Том 11, № 1 (2017)
- Беттер: 43-54
- Бөлім: Article
- URL: https://journals.rcsi.science/1990-7508/article/view/197613
- DOI: https://doi.org/10.1134/S1990750817010036
- ID: 197613
Дәйексөз келтіру
Аннотация
This systematic review was aimed at identification of cancer stem cells (CSC) molecular markers, which was validated in experiments on transplantation of tumor subpopulations with different phenotypes to immunodeficient animals. After careful examination of available papers, we selected 97 reports, fully consistent with the objectives of the study. The results of their analysis show that markers commonly used for CSC isolation include: CD133, СD44, ALDH, CD34, CD24, and EpCAM. The review also contains description of molecular features of some CSC markers; it also considers modern approaches to cancer treatment by targeting this population and evaluates perspectives of further development of the CSC theory.
Негізгі сөздер
Авторлар туралы
Y. Kim
Institute of Biomedical Chemistry
Хат алмасуға жауапты Автор.
Email: yankimhcc@gmail.com
Ресей, ul. Pogodinskaya 10, Moscow, 119121
A. Kaidina
Institute of Biomedical Chemistry
Email: yankimhcc@gmail.com
Ресей, ul. Pogodinskaya 10, Moscow, 119121
J.-H. Chiang
National Cheng Kung University
Email: yankimhcc@gmail.com
Қытай республикасы, Tainan City
K. Yarygin
Institute of Biomedical Chemistry
Email: yankimhcc@gmail.com
Ресей, ul. Pogodinskaya 10, Moscow, 119121
A. Lupatov
Institute of Biomedical Chemistry
Email: yankimhcc@gmail.com
Ресей, ul. Pogodinskaya 10, Moscow, 119121
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