Pharmacological Targets for Correction of Dyslipidemias. Opportunities and Prospects of Therapeutic Use
- Authors: Kudinov V.A.1, Zakharova T.S.1, Torkhovskaya T.I.1, Ipatova O.M.1, Archakov A.I.1
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Affiliations:
- Institute of Biomedical Chemistry (IBMC)
- Issue: Vol 12, No 2 (2018)
- Pages: 96-113
- Section: Article
- URL: https://journals.rcsi.science/1990-7508/article/view/198143
- DOI: https://doi.org/10.1134/S1990750818020075
- ID: 198143
Cite item
Abstract
The review summarizes literature data on existing pharmacological agents and novel drug preparations developed for correction of dyslipidemias and molecular mechanisms of their action. Much attention is paid to analysis of experimental and clinical studies aimed at identification of new pharmacological targets for correction of dyslipidemias and characterization of approaches increasing high density lipoproteins functionality. The implementation of alternative pharmacological agents with new alternative mechanisms of action may improve the effectiveness of traditional treatment in the future.
About the authors
V. A. Kudinov
Institute of Biomedical Chemistry (IBMC)
Email: tz-post@list.ru
Russian Federation, ul. Pogodinskaya 10, Moscow, 119121
T. S. Zakharova
Institute of Biomedical Chemistry (IBMC)
Author for correspondence.
Email: tz-post@list.ru
Russian Federation, ul. Pogodinskaya 10, Moscow, 119121
T. I. Torkhovskaya
Institute of Biomedical Chemistry (IBMC)
Email: tz-post@list.ru
Russian Federation, ul. Pogodinskaya 10, Moscow, 119121
O. M. Ipatova
Institute of Biomedical Chemistry (IBMC)
Email: tz-post@list.ru
Russian Federation, ul. Pogodinskaya 10, Moscow, 119121
A. I. Archakov
Institute of Biomedical Chemistry (IBMC)
Email: tz-post@list.ru
Russian Federation, ul. Pogodinskaya 10, Moscow, 119121
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