Primary screening of candidate RNA biomarkers for diagnostics of prostate cancer
- 作者: Nikitina A.S.1,2, Babenko V.V.1, Babalyan K.A.2, Vasiliev A.O.3, Govorov A.V.3, Prilepskaya E.A.3, Danilenko S.A.1, Selezneva O.V.1, Sharova E.I.1
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隶属关系:
- Federal Research and Clinical Center of Physical-Chemical Medicine
- Moscow Institute of Physics and Technology
- Department of Urology
- 期: 卷 10, 编号 2 (2016)
- 页面: 180-183
- 栏目: Article
- URL: https://journals.rcsi.science/1990-7508/article/view/197262
- DOI: https://doi.org/10.1134/S1990750816020074
- ID: 197262
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详细
Applicability of prostate cancer candidate RNA biomarkers screening in plasma and urine obtained by minimally invasive or noninvasive methods has been demonstrated. In patients with benign prostatic hyperplasia (BPH) significant amounts of RNAs known in the literature as biomarkers associated with prostate cancer have been detected in plasma and urine samples. Detectable amounts of the markers depended on the methods used for transcriptome profiling. Detection of known RNA biomarkers associated with prostate cancer in urine and plasma samples by the RNA-seq method shows its applicability for the search of new RNA biomarkers for minimally invasive diagnostics. However, the fact of the presence of known prostate cancer RNA biomarkers in samples from BPH patients suggests their insufficient specificity and indicates a clear need for further research in this field.
作者简介
A. Nikitina
Federal Research and Clinical Center of Physical-Chemical Medicine; Moscow Institute of Physics and Technology
编辑信件的主要联系方式.
Email: quokka.smiles@gmail.com
俄罗斯联邦, ul. Malaya Pirogovskaya 1a, Moscow, 119435; Dolgoprudnyi
V. Babenko
Federal Research and Clinical Center of Physical-Chemical Medicine
Email: quokka.smiles@gmail.com
俄罗斯联邦, ul. Malaya Pirogovskaya 1a, Moscow, 119435
K. Babalyan
Moscow Institute of Physics and Technology
Email: quokka.smiles@gmail.com
俄罗斯联邦, Dolgoprudnyi
A. Vasiliev
Department of Urology
Email: quokka.smiles@gmail.com
俄罗斯联邦, Moscow
A. Govorov
Department of Urology
Email: quokka.smiles@gmail.com
俄罗斯联邦, Moscow
E. Prilepskaya
Department of Urology
Email: quokka.smiles@gmail.com
俄罗斯联邦, Moscow
S. Danilenko
Federal Research and Clinical Center of Physical-Chemical Medicine
Email: quokka.smiles@gmail.com
俄罗斯联邦, ul. Malaya Pirogovskaya 1a, Moscow, 119435
O. Selezneva
Federal Research and Clinical Center of Physical-Chemical Medicine
Email: quokka.smiles@gmail.com
俄罗斯联邦, ul. Malaya Pirogovskaya 1a, Moscow, 119435
E. Sharova
Federal Research and Clinical Center of Physical-Chemical Medicine
Email: quokka.smiles@gmail.com
俄罗斯联邦, ul. Malaya Pirogovskaya 1a, Moscow, 119435
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