Bilayer permeability during phase transition as an Erlang flow of hydrophilic pores resulting from diffusion in the radius space
- Авторлар: Anosov A.A.1,2, Sharakshane A.A.3, Smirnova E.Y.2, Nemchenko O.Y.2
-
Мекемелер:
- Kotel’nikov Institute of Radio Engineering and Electronics
- Sechenov First Moscow State Medical University
- Plekhanov Russian University of Economics
- Шығарылым: Том 11, № 1 (2017)
- Беттер: 8-16
- Бөлім: Articles
- URL: https://journals.rcsi.science/1990-7478/article/view/213225
- DOI: https://doi.org/10.1134/S1990747816040139
- ID: 213225
Дәйексөз келтіру
Аннотация
The formation of hydrophilic pores in a lipid bilayer during phase transition is described using the Smoluchowski equation with an additional term of the hydrophobic pore source. This term is added to account for defects in lipid packing during phase transition. We assume that the temporal sequence of the pores is a stochastic process, a non-stationary second-order Erlang flow. Flow characteristics depend on the equation solution and determine the formation times of the hydrophilic pores. The calculated distribution of the durations of intervals between hydrophilic pores is in a good agreement with experimental data published before. In the context of this model we describe the influence of poly(ethylene glycol) on the pore formation frequency.
Негізгі сөздер
Авторлар туралы
A. Anosov
Kotel’nikov Institute of Radio Engineering and Electronics; Sechenov First Moscow State Medical University
Хат алмасуға жауапты Автор.
Email: anosov@hotmail.ru
Ресей, ul. Mokhovaya 11, build. 7, Moscow, 125009; ul. Trubetskaya 8, build. 2, Moscow, 119991
A. Sharakshane
Plekhanov Russian University of Economics
Email: anosov@hotmail.ru
Ресей, Stremyanny per. 36, Moscow, 117997
E. Smirnova
Sechenov First Moscow State Medical University
Email: anosov@hotmail.ru
Ресей, ul. Trubetskaya 8, build. 2, Moscow, 119991
O. Nemchenko
Sechenov First Moscow State Medical University
Email: anosov@hotmail.ru
Ресей, ul. Trubetskaya 8, build. 2, Moscow, 119991
Қосымша файлдар
