The phenomenon of atypical DNA comets
- Authors: Zhanataev A.K.1, Anisina E.A.1, Chayka Z.V.1, Miroshkina I.A.1, Durnev A.D.1
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Affiliations:
- Zakusov Research Institute of Pharmacology
- Issue: Vol 11, No 4 (2017)
- Pages: 286-292
- Section: Article
- URL: https://journals.rcsi.science/1990-519X/article/view/212407
- DOI: https://doi.org/10.1134/S1990519X17040113
- ID: 212407
Cite item
Abstract
The phenomenon of atypical DNA comets observed in experiments using DNA-comet assay is described and illustrated. The current hypotheses explaining the nature of atypical DNA comets and our own take on the issue are considered. The practical importance of the registration of atypical DNA comets during the assessment of genotoxicity is discussed.
About the authors
A. K. Zhanataev
Zakusov Research Institute of Pharmacology
Author for correspondence.
Email: azhanataev@yandex.ru
Russian Federation, Moscow, 125315
E. A. Anisina
Zakusov Research Institute of Pharmacology
Email: azhanataev@yandex.ru
Russian Federation, Moscow, 125315
Z. V. Chayka
Zakusov Research Institute of Pharmacology
Email: azhanataev@yandex.ru
Russian Federation, Moscow, 125315
I. A. Miroshkina
Zakusov Research Institute of Pharmacology
Email: azhanataev@yandex.ru
Russian Federation, Moscow, 125315
A. D. Durnev
Zakusov Research Institute of Pharmacology
Email: azhanataev@yandex.ru
Russian Federation, Moscow, 125315