Influence of FtsZ proteins from some mycoplasma species on the division process in Escherichia coli cells
- Authors: Vedyaykin A.D.1, Polinovskaya V.S.1, Sabantsev A.V.1, Khodorkovskii M.A.1, Borchsenius S.N.2, Vishnyakov I.E.1,2
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Affiliations:
- Peter the Great St.Petersburg Polytechnic University
- Institute of Cytology RAS
- Issue: Vol 11, No 5 (2017)
- Pages: 389-398
- Section: Article
- URL: https://journals.rcsi.science/1990-519X/article/view/212465
- DOI: https://doi.org/10.1134/S1990519X17050108
- ID: 212465
Cite item
Abstract
FtsZ is a highly conserved protein that performs one of the key roles in cell division of most prokaryotes. At the present time it is believed that the main role of FtsZ in the cells of the microorganisms studied (Escherichia coli, Bacillus subtilis, etc.) is to control the process of cell wall synthesis at the site of future septum. In this regard, the presence of FtsZ in the cells of mycoplasmas – bacteria that lack the cell wall, looks intriguing. In the present work we investigated the influence of FtsZ proteins of three mycoplasmas – Mycoplasma hominis, Mycoplasma gallisepticum and Acholeplasma laidlawii – on the cytokinesis of E. coli. FtsZ proteins were able to interact with the E. coli division machinery, including inhibiting the cytokinesis process, while demonstrating various patterns of distribution in the cell. The data obtained support the hypothesis that FtsZ plays a significant role in the division of mycoplasma cells.
About the authors
A. D. Vedyaykin
Peter the Great St.Petersburg Polytechnic University
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 195251
V. S. Polinovskaya
Peter the Great St.Petersburg Polytechnic University
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 195251
A. V. Sabantsev
Peter the Great St.Petersburg Polytechnic University
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 195251
M. A. Khodorkovskii
Peter the Great St.Petersburg Polytechnic University
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 195251
S. N. Borchsenius
Institute of Cytology RAS
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 194064
I. E. Vishnyakov
Peter the Great St.Petersburg Polytechnic University; Institute of Cytology RAS
Author for correspondence.
Email: innvish@gmail.com
Russian Federation, St. Petersburg, 195251; St. Petersburg, 194064