Email this article The Role of Dopamine in Primary Headaches
- Authors: Sokolov A.Y.1,2,3, Popova N.S.1, Povarenkov A.S.4, Amelin A.V.5
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Affiliations:
- Valdman Institute of Pharmacology
- Pavlov Institute of Physiology
- Aff5
- St. Petersburg Mariinsky Hospital
- Department of Neurology
- Issue: Vol 12, No 4 (2018)
- Pages: 324-336
- Section: Review Articles
- URL: https://journals.rcsi.science/1819-7124/article/view/211595
- DOI: https://doi.org/10.1134/S1819712418030145
- ID: 211595
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Abstract
We review the role of dopamine in the mechanisms of development of primary headaches, including migraine. Some data are given about the involvement of various types of dopamine receptors in the regulation of cranial blood flow and control of nociceptive transmission in the trigeminal nerve system. We discuss the role of the basal ganglia in the neurobiology of cephalgias. One part of the review is focused on dopaminergic drugs that may be used in the therapy of migraine.
About the authors
A. Y. Sokolov
Valdman Institute of Pharmacology; Pavlov Institute of Physiology; Aff5
Author for correspondence.
Email: alexey.y.sokolov@gmail.com
Russian Federation, St. Petersburg; St. Petersburg; ul. L′va Tolstogo 6–8, St. Petersburg, 197022
N. S. Popova
Valdman Institute of Pharmacology
Email: alexey.y.sokolov@gmail.com
Russian Federation, St. Petersburg
A. S. Povarenkov
St. Petersburg Mariinsky Hospital
Email: alexey.y.sokolov@gmail.com
Russian Federation, St. Petersburg
A. V. Amelin
Department of Neurology
Email: alexey.y.sokolov@gmail.com
Russian Federation, St. Petersburg
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