Recrystallization of CaCO3 submicron magnetic particles in biological media
- Авторлар: Kalinova A.1, Kuznetsova L.1, Ushakov A.1, Popova M.1, Abalymov A.1, Demina P.1, Anisimov R.1, Lomova M.1
-
Мекемелер:
- Saratov State University
- Шығарылым: Том 23, № 4 (2023)
- Беттер: 371-377
- Бөлім: Articles
- URL: https://journals.rcsi.science/1817-3020/article/view/251252
- DOI: https://doi.org/10.18500/1817-3020-2023-23-4-371-377
- EDN: https://elibrary.ru/AKANPR
- ID: 251252
Дәйексөз келтіру
Толық мәтін
Аннотация
Background and Objectives: The development of magnetic theranostics is associated with the determination of the behavior of magnetic carriers in biosimilar media. In this work, we analyze the formation of different crystalline phases from magnetic mineral submicron calcium carbonate particles during incubation under conditions of cell cultivation in vitro for 3 days. The study of mineralmagneticsubmicron particles recrystallization was analyzed by XRD and electron scanning microscopy. The shape of calcium carbonate particles begins to change from elliptical to spherical under cell culture cultivations. As the amount of magnetite nanoparticle particles in calcium carbonate increases, the recrystallization process is faster with fallout of calcite, vaterite and magnetite phases. Materials and Methods: Scanning electron microscopy, processing of results using a self-written Python code, XRDwere utilized in this study. Results: The study of the process of recrystallization of magnetic mineral particles shows has shown that increasing the content of magnetic carriers leads to accelerated recrystallization of particles with simultaneous precipitation of calcite, vaterite and magnetite phases. Conclusion: Magnetic mineral submicron calcium carbonate particles are promising targets for theranostics with the self-destruction property in biological environments.
Негізгі сөздер
Авторлар туралы
Alexandra Kalinova
Saratov State University
Email: skripalav@info.sgu.ru
410012, Russia, Saratov, Astrakhanskaya street, 83
Ludmila Kuznetsova
Saratov State University
Email: skripalav@info.sgu.ru
ORCID iD: 0009-0004-3999-031X
410012, Russia, Saratov, Astrakhanskaya street, 83
Arseni Ushakov
Saratov State University
Email: skripalav@info.sgu.ru
ORCID iD: 0000-0003-0495-7750
Scopus Author ID: 54409932500
ResearcherId: K-3318-2012
410012, Russia, Saratov, Astrakhanskaya street, 83
Maria Popova
Saratov State University
Email: skripalav@info.sgu.ru
410012, Russia, Saratov, Astrakhanskaya street, 83
Anatoliy Abalymov
Saratov State University
Email: skripalav@info.sgu.ru
ORCID iD: 0000-0002-3957-2706
Scopus Author ID: 57190869864
410012, Russia, Saratov, Astrakhanskaya street, 83
Polina Demina
Saratov State University
Email: skripalav@info.sgu.ru
ORCID iD: 0000-0002-9203-582X
Scopus Author ID: 37661275800
ResearcherId: E-9464-2019
410012, Russia, Saratov, Astrakhanskaya street, 83
Roman Anisimov
Saratov State University
Email: skripalav@info.sgu.ru
410012, Russia, Saratov, Astrakhanskaya street, 83
Maria Lomova
Saratov State University
Хат алмасуға жауапты Автор.
Email: skripalav@info.sgu.ru
ORCID iD: 0000-0002-7464-1754
410012, Russia, Saratov, Astrakhanskaya street, 83
Әдебиет тізімі
- Liu D., Yang F., Xiong F., Gu N. The Smart Drug Delivery System and Its Clinical Potential. Theranostics, 2016, vol. 6, iss. 9, pp. 1306–1323. https://doi.org/10.7150/thno.14858
- Ferreira A. M., Vikulina A. S., Volodkin D. V. CaCO3 Crystals as Versatile Carriers for Controlled Delivery of Antimicrobials. J. Controlled Release, 2020, vol. 328, pp. 470–489. https://doi.org/10.1016/j.jconrel.2020.08.061
- Kelkar S. S., Reineke T. M. Theranostics: Combining Imaging and Therapy. Bioconjugate Chemistry, 2011, vol. 22, iss. 10, pp. 1879–1903. https://doi.org/10.1021/bc200151q
- Sharma D., Ali A. A. E., Trivedi L. R. An Updated Review On: Liposomes as Drug Delivery System. Pharmatutor, 2018, vol. 6, iss. 2, pp. 50–62. https://doi.org/10.29161/PT.v6.i2.2018.50
- Fadia P., Tyagi S., Bhagat S., Nair A., Panchal P., Dave H., Dang S., Singh S. Calcium Carbonate Nano- and Microparticles: Synthesis Methods and Biological Applications. 3 Biotech., 2021, vol. 11, pp. 1–30. https://doi.org/10.1007/s13205-021-02995-2
- Liendo F., Arduino M., Deorsola F. A., Bensaid S. Factors Controlling and Influencing Polymorphism, Morphology and Size of Calcium Carbonate Synthesized through the Carbonation Route: A Review. Powder Technol., 2022, vol. 398, no. 117050. https://doi.org/10.1016/j.powtec.2021.117050
- Goswami M. M., Dey C., Bandyopadhyay A., Sarkar D., Ahir M. Micelles Driven Magnetite (Fe3O4) Hollow Spheres and a Study on AC Magnetic Properties for Hyperthermia Application. Journal of Magnetism and Magnetic Materials, 2016, vol. 417, pp. 376–381. https://doi.org/10.1016/j.jmmm.2016.05.069
- Feoktistova N. A., Vikulina A. S., Balabushevich N. G., Skirtach A. G., Volodkin D. Bioactivity of Catalase Loaded into Vaterite CaCO3 Crystals via Adsorption and Co-Synthesis. Materials & Design, 2020, vol. 185, article no. 108223. https://doi.org/10.1016/j.matdes.2019.108223
- Wu C., Liu X., Yao F., Yang X., Wang Y., Hu W. Crystalline-Magnetism Action in Biomimetic Mineralization of Calcium Carbonate. Chinese Journal of Chemical Engineering, 2023, vol. 59, pp. 146–152. https://doi.org/10.1016/j.cjche.2023.01.004
- Ponomar V. Crystal Structures and Magnetic Properties of Spinel Ferrites Synthesized from Natural Fe–Mg– Ca Carbonates. Materials Research Bulletin, 2023, vol. 158, article no. 112068. https://doi.org/10.1016/j.materresbull.2022.112068
- Fakhrullin R. F., Bikmullin A. G., Nurgaliev D. K. Magnetically Responsive Calcium Carbonate Microcrystals. ACS Applied Materials & Interfaces, 2009, vol. 1, iss. 9, pp. 1847–1851. https://doi.org/10.1021/am9003864
- German S. V., Inozemtseva O. A., Markin A. V., Metvalli Kh., Khomutov G. B., Gorin D. A. Synthesis of Magnetite Hydrosols in Inert Atmosphere. Colloid Journal, 2013, vol. 75, iss. 4, pp. 483–486. https://doi.org/10.1134/S1061933X13040042
- Kozlova A. A., German S. V., Atkin V. S., Zyev V. V., Astle M. A., Bratashov D. N., Svenskaya Y. I., Gorin D. A. Magnetic Composite Submicron Carriers with Structure-Dependent MRI Contrast. Inorganics, 2020, vol. 8, iss. 2, article no. 11. https://doi.org/10.3390/inorganics8020011
- German S. V., Novoselova M. V., Bratashov D. N., Demina P. A., Atkin V. S., Voronin D. V., Khlebtsov B. N., Parakhonskiy B. V., Sukhorukov G. B., Gorin D. A. High-Efficiency Freezing-Induced Loading of Inorganic Nanoparticles and Proteins into Micron- and Submicron-Sized Porous Particles. Scientific Reports, 2018, vol. 8, iss. 1, article no. 17763. https://doi.org/10.1038/s41598-018-35846-x
- Atchudan R., Perumal S., Joo J., Lee Y. R. Synthesis and Characterization of Monodispersed Spherical Calcium Oxide and Calcium Carbonate Nanoparticles via Simple Pyrolysis. Nanomaterials, 2022, vol. 12, iss. 14, article no. 2424. https://doi.org/10.3390/nano12142424
![](/img/style/loading.gif)