Modern possibilities of immunotherapy in the treatment of extensive-stage small cell lung cancer: experience of durvalumab application. Case report
- 作者: Zhabina A.1, Moiseenko F.1,2,3, Volkov N.1, Abduloeva N.1, Moiseenko V.1
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隶属关系:
- Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological)
- Petrov National Medical Research Center of Oncology
- Mechnikov North-Western State Medical University
- 期: 卷 23, 编号 2 (2021)
- 页面: 287-291
- 栏目: CLINICAL ONCOLOGY
- URL: https://journals.rcsi.science/1815-1434/article/view/70980
- DOI: https://doi.org/10.26442/18151434.2021.2.200901
- ID: 70980
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详细
Extensive-stage small cell lung cancer (ES-SCLC) is characterized by an aggressive course, a high recurrence rate and fast progression. For a long time, the survival prognosis for the most patients suffering from this disease remained unfavorable. The situation changed with the appearance of chemoimmunotherapy in clinical practice. Chemotherapy based on durvalumab in comparison with the standard chemotherapy demonstrated the statistically and clinically significant increase in median overall survival in patients with previously untreated ES-SCLC in the CASPIAN international trial. This article deals with the case of the application of standard chemotherapy in combination with durvalumab as a first-line ES-SCLC therapy. The patient started receiving durvalumab therapy in June 2017 as a part of the CASPIAN international trial. In March 2021 the duration of therapy was 45 months, the patient had a complete regression of the disease.
作者简介
Albina Zhabina
Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological)
编辑信件的主要联系方式.
Email: albina_zhabina@inbox.ru
ORCID iD: 0000-0001-9749-8519
SPIN 代码: 1724-7764
Cand. Sci. (Med.)
俄罗斯联邦, Saint PetersburgFedor Moiseenko
Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological); Petrov National Medical Research Center of Oncology; Mechnikov North-Western State Medical University
Email: moiseenkofv@gmail.com
ORCID iD: 0000-0003-2544-9042
D. Sci. (Med.)
俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint PetersburgNikita Volkov
Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological)
Email: volkovnm@gmail.com
ORCID iD: 0000-0002-6232-257X
Cand. Sci. (Med.)
俄罗斯联邦, Saint PetersburgNuriniso Abduloeva
Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological)
Email: Abduloeva-n@mail.ru
ORCID iD: 0000-0001-5236-0241
Cand. Sci. (Med.)
俄罗斯联邦, Saint PetersburgVladimir Moiseenko
Saint Petersburg Clinical Scientific and Practical Center for Specialized Types of Medical Aid (oncological)
Email: moiseyenkov@gmail.com
ORCID iD: 0000-0002-2246-0441
D. Sci. (Med.), Prof.
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