Latent herpes virus infection in the carcinogenesis of bladder cancer

O B Loran; Лоран Олег Борисович; L A Sinyakova; Синякова Любовь Александровна; L V Gundorova; Гундорова Людмила Викторовна; V A Kosov; Косов Владимир Алексеевич; I V Kosova; Косова Инга Владимировна; D N Kolbasov; Колбасов Дмитрий Николаевич; I V Kononkov; Кононков Игорь Вячеславович

Latent herpes virus infection in the carcinogenesis of bladder cancer

作者: Loran O¹, Sinyakova L¹, Gundorova L², Kosov V³, Kosova I², Kolbasov D², Kononkov I²
隶属关系:
1. Russian Medical Academy of Postgraduate Education of the Ministry of Health of the Russian Federation
2. City Clinical Hospital №68 of the Department of Health of Moscow
3. Komi Republican Oncologic Hospital
期: 卷 17, 编号 3 (2015)
页面: 96-99
栏目: Articles
URL: https://journals.rcsi.science/1815-1434/article/view/27040
ID: 27040

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This article discusses the basic mechanisms of latency some of the herpes viruses and the role of persistence of these viruses in oncogenesis. A statistically significant increase of the level of viral antibodies in patients with recurrent, locally advanced bladder cancer with high potential of malignancy; the statistically significant correlations between the presence of viral DNA cytomegalovirus and Epstein-Barr virus in the tumor and the level of antibodies, the stage of the process and recurrent nature of the tumor were found. The presence of viral DNA in the tumor was determined in 30% of cases.

关键词

bladder cancer, Epstein-Barr virus, cytomegalovirus, herpes viruses type 1 and 2

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参考

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Latent herpes virus infection in the carcinogenesis of bladder cancer

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详细

关键词

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作者简介

O Loran

L Sinyakova

L Gundorova

V Kosov

I Kosova

D Kolbasov

I Kononkov

参考