Prolongirovannaya blokada angiogeneza pri metastaticheskom kolorektal'nom rake (novye dannye)


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В представленном обзоре обсуждается новая стратегия пролонгированного применения бевацизумаба при метастатическом колоректальном раке. Анализ представленных рандомизированных исследований показал, что после инициального назначения препарата одновременно с более интенсивным химиотерапевтическим режимом целесообразно переходить на поддерживающее лечение бевацизумабом ± фторпиримидин. Введение бевацизумаба необходимо продолжать до прогрессирования болезни. При прогрессировании процесса продолжение бевацизумаба со сменой режима химиотерапии достоверно увеличивает показатели выживаемости и имеет преимущества перед другими терапевтическими опциями.

作者简介

E Artamonova

ФГБУ РОНЦ им. Н.Н.Блохина РАМН, Москва

д-р мед. наук, вед. науч. сотр.

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