Факторы прогноза при раке молочной железы

  • Авторы: Божок АА1, Семиглазов ВФ1, Семиглазов ВВ2, Арзуманов АС3, Клетсель АЕ4
  • Учреждения:
    1. ГУН НИИ онкологии им. проф. Н.Н.Петрова, Санкт-Петербург
    2. Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова
    3. Центральный научно-исследовательский рентгенорадиологический институт, Санкт-Петербург
    4. Клиника онкологии и гинекологии, Оснабрюк, Германия
  • Выпуск: Том 7, № 1 (2005)
  • Страницы: 4-9
  • Раздел: Статьи
  • URL: https://journals.rcsi.science/1815-1434/article/view/26566
  • ID: 26566

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Аннотация

Основная задача адъювантного лечения при раке молочной железы (РМЖ) - максимальный эффект при минимальных токсических воздействиях. Она разрешима только путем индивидуализации терапии, т.е. с учетом факторов, предсказывающих эффект от лечения и прогноз течения заболевания. До сих пор выбор адъювантного лечения основывался на учете степени местно-регионарного распространения опухоли (система TNM), уровня экспрессии рецепторов к стероидным гормонам и репродуктивном статусе (или, чаще, возрасте) больных. Как показывают результаты клинических исследований, этой информации недостаточно для планирования адекватного лечения. Настоящая статья посвящена обзору имеющейся информации о значении различных молекулярных маркеров для определения прогноза и выбора терапии при РМЖ.

Об авторах

А А Божок

ГУН НИИ онкологии им. проф. Н.Н.Петрова, Санкт-Петербург

В Ф Семиглазов

ГУН НИИ онкологии им. проф. Н.Н.Петрова, Санкт-Петербург

В В Семиглазов

Санкт-Петербургский государственный медицинский университет им. акад. И.П.Павлова

А С Арзуманов

Центральный научно-исследовательский рентгенорадиологический институт, Санкт-Петербург

А Е Клетсель

Клиника онкологии и гинекологии, Оснабрюк, Германия

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