Prognostic relevance of the TNM classification 8th edition and new criteria of staging for retroperitoneal liposarcoma
- Authors: Nered S.N.1,2, Volkov A.Y.1, Kozlov N.А.1, Stilidi I.S.1,2, Archery P.P.1,2
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Affiliations:
- Blokhin National Medical Research Center of Oncology
- Russian Medical Academy of Continuous Professional Education
- Issue: Vol 22, No 3 (2020)
- Pages: 120-126
- Section: Original Article
- URL: https://journals.rcsi.science/1815-1434/article/view/52596
- DOI: https://doi.org/10.26442/18151434.2020.3.200220
- ID: 52596
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Abstract
For the first time a section appeared for staging of non-organ retroperitoneal tumors in the UICC TNM classification 8th edition.
Aim. To assess the prognostic significance of the TNM classification eighth edition for the most common retroperitoneal tumors-liposarcoma.
Materials and methods. The distribution of patients by stages and survival in accordance with the TNM-8 classification were studied in 192 patients with retroperitoneal non-organ liposarcoma (RLPS).
Results. In the TNM-8 classification, only the degree of malignancy of the tumor has a prognostic value, and the T-category does not reflect the actual size of the RLPS and is considered T4 in 93%, which leads to inadequate staging. During the 15-year period, there were no cases with stages II and IIIA, and the survival rate was estimated only in patients with stages I and IIIB. A TNM classification with new values of the T-category was proposed, which demonstrated a more adequate distribution of patients by stages and the reliability of intergroup differences in the survival rate.
Conclusion. It is advisable to create a special TNM classification for RLPS, which makes up more than half of all retroperitoneal sarcomas.
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##article.viewOnOriginalSite##About the authors
S. N. Nered
Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education
Email: nered@mail.ru
SPIN-code: 4588-3230
D. Sci. (Med.), Prof., Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education
Russian Federation, MoscowA. Yu. Volkov
Blokhin National Medical Research Center of Oncology
Email: 79164577128@yandex.ru
ORCID iD: 0000-0003-4412-2256
SPIN-code: 3013-4392
Graduate Student, Blokhin National Medical Research Centre of Oncology
Russian Federation, MoscowN. А. Kozlov
Blokhin National Medical Research Center of Oncology
Email: newbox13@mail.ru
SPIN-code: 1847-6530
Cand. Sci. (Med.), Blokhin National Medical Research Centre of Oncology
Russian Federation, MoscowI. S. Stilidi
Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education
Author for correspondence.
Email: istilidi@front.ru
SPIN-code: 9622-7106
D. Sci. (Med.), Prof., Acad. RAS, Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education
Russian Federation, MoscowP. P. Archery
Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education
Email: arhiri@mail.ru
SPIN-code: 6880-4902
Cand. Sci. (Med.), Blokhin National Medical Research Centre of Oncology, Russian Medical Academy of Continuous Professional Education
Russian Federation, MoscowReferences
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