Case studies on clinical experience of targeted therapy ribociclib in combination with letrozole in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer

M A Frolova; Фролова Мона Александровна; Ya I Kochetkova; Кочеткова Яна Игоревна; V A Chubenko; Чубенко Вячеслав Андреевич; N M Volkov; Волков Никита Михайлович; F V Moiseenko; Моисеенко Федор Владимирович; T V Garmarnik; Гармарник Татьяна Валерьевна; D M Ponomarenko; Пономаренко Дмитрий Михайлович; A E Orlov; Орлов Андрей Евгеньевич; Yu V Kostalanova; Косталанова Юлия Владимировна; Yu Yu Makarycheva; Макарычева Юлия Юрьевна; A A Nizegorodzeva; Нижегородцева Александра Анатольевна

doi:10.26442/1815-1434_2018.2.29-37

Case studies on clinical experience of targeted therapy ribociclib in combination with letrozole in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer

Authors: Frolova MA¹, Kochetkova Y.I¹, Chubenko VA², Volkov NM³, Moiseenko FV⁴, Garmarnik TV⁵, Ponomarenko DM⁶, Orlov AE⁷, Kostalanova Y.V⁸, Makarycheva Y.Y.⁸, Nizegorodzeva AA⁸
Affiliations:
1. ФГБУ «НМИЦ онкологии им. Н.Н.Блохина»
2. ГБУЗ СПб КНпЦСВМП(о)
3. НИИ онкологии им. Н.Н.Петрова
4. ФГБОУ ВО «СЗГМУ им. И.И.Мечникова», СПб КНпЦСВМП(о)
5. ГБУЗ КО КОКОД
6. ГБУЗ ООД
7. ФГБОУ ВО СамГМУ
8. ГБУЗ СОКОД
Issue: Vol 20, No 2 (2018)
Pages: 29-37
Section: Articles
URL: https://journals.rcsi.science/1815-1434/article/view/29547
DOI: https://doi.org/10.26442/1815-1434_2018.2.29-37
ID: 29547

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Abstract

The article represents case studies on clinical experience of targeted therapy ribociclib in combination with letrozole in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer in Russian Federation. Russian oncologists’ experience has demonstrated the high efficacy and manageable safety profile of the ribociclib treatment in patients in clinical practice.