Dermatomyositis and polymyositis in breast cancer patients: a case reports

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Abstract

Dermatomyositis and polymyositis are an autoimmune disease which is characterized by proximal skeletal muscle weakness, muscle inflammation and associated with a variety of skin manifestations. Both autoimmune conditions are mainly observed as an independent disease, though an association between dermato- and polymyositis and malignancy were described. Case reports of two patients are presented, in one of which dermatomyositis and breast cancer were manifested simultaneously, in the other - the development of polymyositis preceded the recurrence of the disease after a long-term remission. Also diagnostic and therapeutic options of both conditions are shown.

About the authors

I P Ganshina

N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

канд. мед. наук, вед. науч. сотр. отд-ния химиотерапии и комбинированного лечения злокачественных опухолей 115478, Russian Federation, Moscow, Kashirskoe sh., d. 23

L G Zhukova

N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

д-р мед. наук, зав. отд-нием химиотерапии и комбинированного лечения злокачественных опухолей 115478, Russian Federation, Moscow, Kashirskoe sh., d. 23

E Z Burnevitch

I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

Email: ganshinainna77@mail.ru
канд. мед. наук, доцент каф. внутренних, профессиональных болезней и пульмонологии 119991, Russian Federation, Moscow, ul. Trubetskaia, d. 8, str. 2

O O Gordeeva

N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

аспирант отд-ния химиотерапии и комбинированного лечения злокачественных опухолей 115478, Russian Federation, Moscow, Kashirskoe sh., d. 23

O E Kondratieva

N.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation

ординатор отд-ния химиотерапии и комбинированного лечения злокачественных опухолей 115478, Russian Federation, Moscow, Kashirskoe sh., d. 23

References

  1. Dalakas M.C, Hohlfeld R. Polymyositis and dermatomyositis. Lancet 2003; 362 (9388): 971.
  2. Zantos D, Zhang Y, Felson D. The overall and temporal association of cancer with polymyositis and dermatomyositis. J Rheumatol 1994; 21: 1855-9.
  3. Barnes B.E, Mawr B. Dermatomyositis and malignancy. A review of the literature. Ann Intern Med 1976; 84 (1): 68.
  4. Sigurgeirsson B, Lindelöf B et al. Risk of cancer in patients with dermatomyositis or polymyositis. A population-based study. N Engl J Med 1992; 326 (6): 363.
  5. Rai S.K, Choi H.K et al. Risk of myocardial infarction and ischaemic stroke in adults with polymyositis and dermatomyositis: a general population-based study. Rheumatology (Oxford). 2016; 55 (3): 461-9. Epub 2015 Sep 30.
  6. Mimori T, Imura Y et al. Autoantibodies in idiopathic inflammatory myopathy: an update on clinical and pathophysiological significance. Curr Opin Rheumatol 2007; 19 (6): 523.
  7. Brouwer R, Hengstman G.J. et al. Autoantibody profiles in the sera of European patients with myositis. Ann Rheum Dis 2001; 60 (2): 116.
  8. Koenig M, Fritzler M.J et al. Heterogeneity of autoantibodies in 100 patients with autoimmune myositis: insights into clinical features and outcomes. Arthritis Res Ther 2007; 9 (4): R78.
  9. Колядина И.В., Поддубная И.В. Современные возможности терапии HER2-положительного рака молочной железы (по материалам клинических исследований). Современ. онкология. 2014; 4: 10-21.
  10. Колядина И.В., Поддубная И.В. и др. Гетерогенность рака молочной железы I стадии: биологическое и прогностическое значение. Злокачественные опухоли. 2015; 1: 31-42.
  11. Hendren E, Vinik O. Breast cancer and dermatomyositis: a case study and literature review. Curr Oncol 2017; 24 (5): e429-e433.

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