The clinical relevance of flow cytofluorometry in the diagnosis of malignant non-Hodgkins lymphoma

The purpose of the study was in defining of the role of immunophenotyping (IPT) by flow cytometry in the lymphoproliferative diseases differential diagnosis. There was analysis of the results of laboratory studies of peripheral blood and bone marrow hematopoietic punctates of 630 patients. 236 patients were under observation by hematologists previously for chronic lymphocytic leukemia (CLL) - the first group; 394 patients were first directed to excluding the non-Hodgkin's lymphoma (NHL) - the second group. The NHL was first detected in 30 examined patients (12.7%) after IPT in the first group of patients. The NHL was detected in 12 examined patients (3.05%) in the second group of patients. Thus, using of the IPT significantly improves the quality of diagnosis NHL that ensures the efficacy of further therapy.

ductal cytofluorometry, non-Hodgkin's lymphoma, lymphoproliferative diseases