Comparative analysis of oral fluid metabolism parameters between patients with complicated and uncomplicated implantation

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ВACKGROUND: Modern scientific research continues to develop promising areas for diagnosing inflammatory complications after dental implantation. Analysis of studies shows that inflammatory complications depend on various factors, the establishment of which can be challenging. Hence, saliva diagnostics opens up broad prospects for studying the pathogenetic basis of the development of inflammatory processes.

АIM: To study in a comparative aspect the metabolic status of complicated and uncomplicated implantation.

MATERIALS AND METHODS: This study examined 88 patients (30 with peri-implant mucositis [main group I], 28 with uncomplicated implantation [comparison group II], and 30 controls [control group]) aged 45.3±2.4 years who were followed up for 1–3 years.

RESULTS: Based on the results of the studies and comparative analysis of complicated and uncomplicated implantation, previously unknown data on their distinctive metabolic characteristics were obtained and presented. With complicated implantation, these include a characteristic increase in C-reactive protein, iron, and uric acid and a decrease in calcium levels.

CONCLUSION: New information revealing prognostically significant factors of gastric cancer metabolism during complicated and uncomplicated implantation has been obtained. The identified changes in metabolism during implantation should be considered and differentiated from early metabolic signs of inflammation. The study of oral fluid is objective and promising in the diagnosis of the inflammatory process and its prognosis.

作者简介

Vladimir Tlustenko

Samara State Medical University

Email: vlastt@yandex.ru
ORCID iD: 0000-0002-7429-9135
SPIN 代码: 8537-5155

MD, Cand. Sci. (Medicine), Associate Professor

俄罗斯联邦, Samara

Vladimir Koshelev

Samara State Medical University

编辑信件的主要联系方式.
Email: stomvk@yandex.ru
ORCID iD: 0000-0001-8479-0342
SPIN 代码: 6886-6628
俄罗斯联邦, Samara

Valentina Tlustenko

Samara State Medical University

Email: stas-763@yandex.ru
ORCID iD: 0000-0002-2756-5277
SPIN 代码: 2737-9657

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Samara

Alexandr Ivashenko

Samara State Medical University

Email: a.v.ivaschenko@samsmu.ru
ORCID iD: 0000-0002-2965-963X
SPIN 代码: 5066-8179

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Samara

参考

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1. JATS XML
2. Fig. 1. Graphical diagram of the integral indicator: а — total protein; b — albumin; * extrema values spaced from the edge of the box by three of its lengths.

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3. Fig. 2. Graphical diagram of the integral indicator: а — uric acid; b — C-reactive protein; *, ** extrema values spaced from the edge of the box by three of its lengths.

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4. Fig. 3. Graphical diagram of the integral indicator: а — cholesterol; b — iron; ** extrema values spaced from the edge of the box by three of its lengths.

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5. Fig. 4. Graphical diagram of the integral indicator: а — calcium; b — phosphorus; * extrema values spaced from the edge of the box by three of its lengths.

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6. Fig. 5. Graphical diagram of the integral indicator: а — sodium; b — potassium.

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7. Fig. 6. Graphical diagram of the integrated indicator of chlorine content; * extrema values spaced from the edge of the box by three of its lengths.

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