Clinical characteristics of sialadenosis in patients with omegapenia before and after treatment
- Authors: Afanasjev V.V.1, Tseloev M.M.1
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Affiliations:
- A.I. Yevdokimov Moscow State University of Medicine and Dentistry
- Issue: Vol 25, No 5 (2021)
- Pages: 409-414
- Section: Clinical Investigation
- URL: https://journals.rcsi.science/1728-2802/article/view/109165
- DOI: https://doi.org/10.17816/1728-2802-2021-25-5-409-414
- ID: 109165
Cite item
Abstract
BACKGROUND: Sialadenoses are often diagnosed as concomitant with certain human diseases. At the initial disease stage, it is not always possible to establish the causative pathological process. Omega-3 fatty acids have great effects on humans. The most important omega-3 fatty acids are actively involved in the metabolism, are the building materials of cells, and help in the prevention of certain diseases.
AIM: The omega-3 levels in 20 patients were examined. Moreover, levels of omega-3 in 20 patients with sialadenosis were measured before and after treatment with omega-3 to determine the functional activity of the salivary glands depending on the concentrations in the tissues.
MATERIAL AND METHODS: Polyunsaturated omega-3 fatty acid is the collective name of several fatty acids; although they are not synthesized in the right quantities in humans, they are necessary for maintaining health. The most important omega-3 fatty acids are actively involved in the metabolism and help in the prevention of cardiovascular diseases, depression, and impaired tissue microcirculation, substantially affecting the human body.
RESULTS: The omega-3 index before treatment was significantly reduced in all patients with sialadenosis, and it significantly increased (p ≤0.001) after treatment in both women and men. Moreover, the secretory function of the salivary glands significantly improved, the viscosity decreased, and the pH of the mixed saliva was restored.
CONCLUSION: The results of this study revealed normalization of the omega-3 index level in the erythrocyte membrane after treatment with omega-3, improvement of the secretory activity of the salivary glands, reduction of viscosity, and restoration of the pH of mixed saliva.
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##article.viewOnOriginalSite##About the authors
Vasiliy V. Afanasjev
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Author for correspondence.
Email: prof.afanasjev@yandex.ru
ORCID iD: 0000-0002-9156-7883
MD, Dr. Sci. (Med.), Professor
Russian Federation, 20, buil. 1, Delegatskaya str., MoscowMagomed M. Tseloev
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Email: magha.2011@mail.ru
ORCID iD: 0000-0002-2847-4262
postgraduate student
Russian Federation, 20, Delegatskaya str., buil. 1, MoscowReferences
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