Positive effect of autologous immune peptides applications in the surgical treatment of inflammatory-destructive periodontal lesions


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Abstract

Clinical efficacy of autologous complex immune peptides (ACIP) shown in patients with inflammatory and destructive periodontal lesions. The level of gene recognition expression receptors of innate immunity (TLR4) was studied and beta-defensin (hBD-3) periodontal mucosal epithelial cells and TGF b-1 concentration in gingival fluid. Innate immunity factors analysis was spend before and after surgery using osteoplastic material (ACIP) in dynamics. ACIP immune regulatory effect on the performance of innate immunity was shown.

About the authors

Oksana Aleksandrovna Zorina

Federal State Institution Central Research Institute of Dental and Maxillofacial Surgery Ministry of Health of Russia; «I.M. Sechenov First Moscow State Medical University» the Ministry of Health of Russia

Author for correspondence.
Email: zorina-cniis@yandex.ru

Dr. Med. Sci., head the Department of operative dentistry Federal Research institute of stomatology and maxillo-facial surgery, Professor of dentistry «I.M.Sechenov First MSMU»

Moscow

L. V Gankovskaya

N.I. Pirogov Federal Russian national medical University

Email: info@eco-vector.com
Moscow

R. A Balykin

Federal State Institution Central Research Institute of Dental and Maxillofacial Surgery Ministry of Health of Russia

Email: info@eco-vector.com
Moscow

T. P Ivanyushko

«I.M. Sechenov First Moscow State Medical University» the Ministry of Health of Russia

Email: info@eco-vector.com
Moscow

O. A Svitich

«I.M. Sechenov First Moscow State Medical University» the Ministry of Health of Russia; N.I. Pirogov Federal Russian national medical University

Email: info@eco-vector.com
Moscow

V. V Grechenko

N.I. Pirogov Federal Russian national medical University

Email: info@eco-vector.com
Moscow

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