SEVEN-YEAR SURVIVAL AND ASSOCIATIONS OF RISK FACTORS WITH ALL-CAUSE AND CARDIOVASCULAR MORTALITY AMONG RURAL RESIDENTS OF SAMARA REGION

Introduction: The high prevalence of behavioral risk factors in Russia has a significant impact on the health of the population being a serious threat for both current and future generations. There is substantial evidence on heath differences between and within countries. Aim: To estimate the 7-year survival rate and the association between risk factors and all-cause and cardiovascular mortality among rural residents of the Samara region of Russia. Methods: This is a prospective cohort study conducted in the framework of the "Interepid» international project. The analysis included the data from a representative sample of the 20-64 years old rural residents of the Volzhsky district of the Samara region of the Russian Federation (n=1050). A cross-sectional survey was carried out in 2011-2012. Vital status and deaths from all causes and from cardiovascular diseases were analyzed twice, after 4 years and after 7 years of the follow-up. Results: Smoking, hypertension, excess intake of meat offal, whole milk and yogurt were significantly associated with all-cause mortality among men while hypertension and obesity were the main contributors to all-cause mortality among women. CVD mortality was associated with smoking, hypertension, excess salt intake, excess intake of meat offal among men while hypertension, low physical activity and excess salt were the main risk factors among women. Conclusions: We observed significant contribution of many risk factors to all-cause and CVD mortality over a 7-year follow-up period. The importance of the risk factors significantly varied across genders. The results of the study can be used in planning, implementation and evaluation of the effectiveness of public health interventions.

risk factors, mortality, prospective study, rural population