Mental ecology in the social challenges’ age: focus on the depressive and anxiety disorders’ comorbidity

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Abstract

This review presents a systematization of information on the clinical characteristics of comorbidity of depressive and anxiety disorders, including stress-associated disorders, taking into the framework of mental ecology’s paradigm. It explores the key issues of etiopathogenetic models and ways to optimize personalized therapy for this category of patients, aimed at reducing medical and social risks and strengthening mental health in the face of modern social challenges. The methodological basis for the work was the materials of the World Health Organization (WHO) and the open sources of the Scopus and Web of Science databases on the problems of comorbidity, depression and anxiety disorders. The analysis included studies with quantitative data, including systematic reviews and meta-analyses. Taking into account the growth of scientific activity, an analysis of both published articles and preprints in Russian and English was carried out. The search was carried out using combinations of keywords and a control vocabulary query covering the terms: mental ecology, comorbidity, depression, anxiety disorders, stress, post-traumatic stress disorder, personalized treatment. To assess the medical and social risks, a search was also carried out on alcohol dependence and alcohol abuse, a common problem among this group of patients.

About the authors

Anna V. Vasileva

National Medical Research Center for Psychiatry and Neurology named after V.M. Bekhterev; North-Western State Medical University named after I.I. Mechnikov

Email: annavdoc@yahoo.com
ORCID iD: 0000-0002-5116-836X
SPIN-code: 2406-9046

MD, Dr. Sci. (Medicine), Associate Professor

Russian Federation, Saint Petersburg; Saint Petersburg

Tatiana A. Karavaeva

National Medical Research Center for Psychiatry and Neurology named after V.M. Bekhterev; Saint-Petersburg State University; Saint-Petersburg State Pediatric Medical University; N.N. Petrov National Medical Research Centre of Oncology

Email: tania_kar@mail.ru
ORCID iD: 0000-0002-8798-3702
SPIN-code: 4799-4121

MD, Dr. Sci. (Medicine), Associate Professor

Russian Federation, Saint Petersburg; Saint Petersburg; Saint Petersburg; Saint Petersburg

Dmitriy S. Radionov

National Medical Research Center for Psychiatry and Neurology named after V.M. Bekhterev

Author for correspondence.
Email: dumradik@mail.ru
ORCID iD: 0000-0001-9020-3271
SPIN-code: 3247-3178
Russian Federation, Saint Petersburg

Diana A. Starunskaya

National Medical Research Center for Psychiatry and Neurology named after V.M. Bekhterev

Email: dianastarunskaya@gmail.com
ORCID iD: 0000-0001-8653-8183
SPIN-code: 1478-0297
Russian Federation, Saint Petersburg

Alexsandra E. Andrianova

National Medical Research Center for Psychiatry and Neurology named after V.M. Bekhterev

Email: alexsandra0013@gmail.com
ORCID iD: 0009-0009-9024-5960
SPIN-code: 2431-1397
Russian Federation, Saint Petersburg

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