Relationship between meteorological factors and the pituitary-thyroid axis in healthy men living in the Subarctic
- Authors: Molodovskaya I.N.1, Tipisova E.V.1, Elfimova A.E.1, Alikina V.A.1, Zyabisheva V.N.1, Tipisov I.N.2
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Affiliations:
- N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
- Northern (Arctic) Federal University named after M.V. Lomonosov
- Issue: Vol 30, No 10 (2023)
- Pages: 781-789
- Section: ORIGINAL STUDY ARTICLES
- URL: https://journals.rcsi.science/1728-0869/article/view/263357
- DOI: https://doi.org/10.17816/humeco623701
- ID: 263357
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Abstract
BACKGROUND: The changing seasons in the subarctic region causes an adaptive restructuring of the inhabitants’ organisms. The most healthy individuals can adjust to the Northern climate without developing health disorders. However, a decrease in adaptive reserves may result in various pathological conditions. Extensive studies across different populations in various climatic zones have reported significant associations between meteorological factors and the fluctuations in thyroid hormones.
AIM: To assess the influence of circannual dynamics of meteorological factors on the serum levels of thyroid hormones and thyroxin-binding globulin (TBG) in men living in subarctic environmental conditions.
MATERIAL AND METHODS: An prospective analytical study was conducted in the city of Arkhangelsk (64°32´24.4˝ N). Twenty clinically healthy men comprised the sample. Blood samples were collected every 3 months over a 12-months period. Subjects with any factors affecting the hypothalamic-pituitary-thyroid axis were excluded. Circannual variation in the studied characteristics were analyzed using Wilcoxon signed-rank tests with Bonferroni correction. Associations between hormonal data and climatic data were assessed using Spearman’s correlation coefficients.
RESULTS: The thyroid-stimulating hormone reached its peak, while T4 and TBG were at their lowest during the period of minimal daylight hours in December. This coincided with the highest values of relative humidity and atmospheric pressure. Furthermore, T4 and TBG positively correlated with the duration of daylight and outdoor temperature at the day of samples collection, while showing an inverse correlation with atmospheric pressure and average monthly relative humidity. Т3 and T4 inversely correlated with average monthly atmospheric pressure. T3 was positively associated with the duration of daylight.
CONCLUSION: The key environmental factors affecting the health people living in Northern regions include are the duration of daylight, outdoor temperature, monthly atmospheric pressure, and relative humidity. It is important to note that the impact of these climatic conditions on human health varies across the regions. Thus, our findings cannot be generalized to other areas..
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##article.viewOnOriginalSite##About the authors
Irina N. Molodovskaya
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Author for correspondence.
Email: pushistiy-86@mail.ru
ORCID iD: 0000-0003-3097-9427
SPIN-code: 2220-1377
Scopus Author ID: 57140775500
Cand. Sci. (Biology)
Russian Federation, ArkhangelskElena V. Tipisova
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Email: tipisova@rambler.ru
ORCID iD: 0000-0003-2097-3806
SPIN-code: 9490-2026
Scopus Author ID: 8704657200
ResearcherId: J-5064-2018
Dr. Sci. (Biology)
Russian Federation, ArkhangelskAleksandra E. Elfimova
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Email: a.elfimova86@mail.ru
ORCID iD: 0000-0003-2519-1600
SPIN-code: 2725-3295
Scopus Author ID: 57140827000
Cand. Sci. (Biology)
Russian Federation, ArkhangelskViktorija A. Alikina
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Email: victoria-popcova@yandex.ru
ORCID iD: 0000-0002-0818-7274
SPIN-code: 2351-1080
Scopus Author ID: 57140412000
Cand. Sci. (Biology)
Russian Federation, ArkhangelskValentina N. Zyabisheva
N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Email: razvalush@yandex.ru
ORCID iD: 0000-0001-6133-8249
SPIN-code: 4062-8845
Russian Federation, Arkhangelsk
Ivan N. Tipisov
Northern (Arctic) Federal University named after M.V. Lomonosov
Email: mr.tipisov@mail.ru
ORCID iD: 0009-0000-7702-1385
SPIN-code: 3701-5716
Student of NARFU named after M.V. Lomonosov
Russian Federation, ArkhangelskReferences
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