Study profile: oral health assessment among participants of “Epidemiology of cardiovascular diseases in Russian regions. Third study” in the Arkhangelsk region

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Abstract

RATIONALE AND AIMS: The population of North Russia has a high prevalence of both cardiovascular and dental diseases. The Arkhangelsk region was included in the third phase of the multicenter study entitled “Epidemiology of cardiovascular diseases in Russian regions. Third study” (“ESSE-RF3’’). The ESSE-RF3 study studied the prevalence of cardiovascular diseases, their biological and behavioral risk factors, and the associations with regional economic, climatic, and geographical characteristics. The Arkhangelsk part of the study is unique as it involved an assessment of the oral health of the ESSE-RF3 study participants. The oral health study protocol is presented in this paper.

METHODS: A population-based study was performed from February 24 through June 30 in the year 2021 at the outpatient facility of the Northern State Medical University in Arkhangelsk. A representative sample of 1816 permanent residents of the Arkhangelsk region aged 35–74 years participated in the ESSE-RF3 study. Most of them (84.9–87.5%) agreed to take part in the oral phase of the study, which included the use of a questionnaire, the collection of oral and gingival crevicular fluid, assessment of dental and periodontal health status using a WHO (2013) methodology; oral hygiene and dental aesthetic index; an orthodontic assessment with periotestometry and a photo protocol. In addition, an in-depth orthodontic study was performed on a sub-sample of the participants aged 35–51 years (n=236) using teleroentgenography, cone-beam computed tomography, and biometrics of the plaster models.

EXPECTED RESULTS AND CONCLUSIONS: The study will assess the prevalence of a wide range of states and conditions related to oral health in a representative sample of the adult population of the Arkhangelsk region in the target age-group using validated international instruments to ensure comparability and reproducibility of the findings. More importantly, the study will assess the associations between various aspects of oral health and cardiovascular diseases, their risk factors as well as regional and behavioral characteristics studied by the main ESSE-RF3 study protocol.

About the authors

Sergei N. Drachev

UiT The Arctic University of Norway; Northern State Medical University

Author for correspondence.
Email: sergei.n.drachev@uit.no
ORCID iD: 0000-0002-1548-690X
SPIN-code: 3879-8612

Cand. Sci. (Med.), MPH, PhD, associate professor, researcher

Norway, Tromsø; Arkhangelsk, Russian Federation

Vyacheslav A. Popov

Northern State Medical University

Email: nka-nenec@yandex.ru
ORCID iD: 0000-0002-5218-437X
SPIN-code: 5066-2100

MPH, assistant lecturer

Russian Federation, Arkhangelsk

Anna A. Simakova

Northern State Medical University

Email: doctororto@yandex.ru
ORCID iD: 0000-0001-8883-9254
SPIN-code: 2971-2925

assistant lecturer

Russian Federation, Arkhangelsk

Maria A. Gorbatova

Northern State Medical University

Email: marigora@mail.ru
ORCID iD: 0000-0002-6363-9595
SPIN-code: 7732-0755

Cand. Sci. (Med.), MPH, associate professor

Russian Federation, Arkhangelsk

Alexander V. Kudryavtsev

UiT The Arctic University of Norway; Northern State Medical University

Email: ispha09@gmail.com
ORCID iD: 0000-0001-8902-8947
SPIN-code: 9296-2930

PhD

Norway, Tromsø; Arkhangelsk, Russian Federation

Leonid L. Shagrov

Northern State Medical University

Email: leonidshagrov@mail.ru
ORCID iD: 0000-0003-2655-9649
SPIN-code: 3842-2145
Russian Federation, Arkhangelsk

Daria A. Popova

Northern State Medical University

Email: dariadent@yandex.ru
ORCID iD: 0000-0002-3570-5161
SPIN-code: 2496-8204

MPH, assistant lecturer

Russian Federation, Arkhangelsk

Andrej M. Grjibovski

Northern State Medical University; Northern (Arctic) Federal University named after M.V. Lomonosov; West Kazakhstan Marat Ospanov State Medical University; Al-Farabi Kazakh National University

Email: andrej.grjibovski@gmail.com
ORCID iD: 0000-0002-5464-0498
SPIN-code: 5118-0081

MD, MPhil, PhD

Russian Federation, Arkhangelsk; Arkhangelsk; Aktobe, Kazakhstan; Almaty, Kazakhstan

Anna V. Kontsevaya

National Medical Research Center for Therapy and Preventive Medicine

Email: akontsevaya@gnicpm.ru
ORCID iD: 0000-0003-2062-1536
SPIN-code: 6787-2500

MD, Dr. Sci. (Med.), associate professor

Russian Federation, Moscow

Tatiana N. Yushmanova

Northern State Medical University

Email: yushmanowa.tatiana@yandex.ru
ORCID iD: 0000-0002-4476-9546
SPIN-code: 3549-8593

Dr. Sci. (Med.), professor

Russian Federation, Arkhangelsk

Lyubov N. Gorbatova

Northern State Medical University

Email: info@nsmu.ru
ORCID iD: 0000-0003-0675-3647
SPIN-code: 8037-5341

Dr. Sci. (Med.), professor

Russian Federation, Arkhangelsk

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2. Fig. 1. Selecting participants in the study “Epidemiology of cardiovascular diseases in Russian regions. The third study” (ESSE-RF3). Here: KYH — “Know your heart”; * conservative response rate calculated as the proportion of the examined persons from the total sample; ** liberal response rate calculated as the proportion of the examined persons from those who were contacted (n=1923).

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3. Fig. 2. Health assessment among ESSE-RF3 participants in the Arkhangelsk Region. Here: BP — blood pressure; HR — heart rate; ECG — electrocardiography. Approximate time in minutes is given.

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4. Fig. 3. Statistical power of logistic regression models to identify the odds ratio of 1.5 and higher for outcome prevalence from 10 to 90% and risk factor prevalence of 10, 25, 50, 75, and 90% in a sample of 1580 people.

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5. Fig. 4. Statistical power of logistic regression models to identify the odds ratio of 2.0 and higher for outcome prevalence from 10 to 90% and risk factor prevalence of 10, 25, 50, 75, and 90% in a sample of 1580 people.

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Copyright (c) 2022 Drachev S.N., Popov V.A., Simakova A.A., Gorbatova M.A., Kudryavtsev A.V., Shagrov L.L., Popova D.A., Grjibovski A.M., Kontsevaya A.V., Yushmanova T.N., Gorbatova L.N.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
 


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