Biophysical parameters of the greater omentum after experimental extended liver resection
- 作者: Leonov S.1, Panchenkov D.2, Rodin A.3
-
隶属关系:
- О.К. Skobelkin State Scientific Center of Laser Medicine
- Moscow State Medical and Dental University named after A.I. Evdokimov
- Smolensk State Medical University
- 期: 卷 24, 编号 3 (2022)
- 页面: 505-510
- 栏目: Research paper
- URL: https://journals.rcsi.science/1682-7392/article/view/108597
- DOI: https://doi.org/10.17816/brmma108597
- ID: 108597
如何引用文章
详细
Bioimpedance parameters of the large omentum after performing extensive liver resection in an experiment were evaluated. The study was performed on 20 Wistar rats that underwent median laparotomy under anesthesia, followed by liver resection with the removal of 70% of the organ. Invasive bioimpedance measurement of the liver and large omentum was performed before and immediately after extensive liver resection on days 3 and 14 after surgery using an original device for measuring the electrical impedance of biological tissues “BIM-II” at frequencies of 2 and 20 kHz with the calculation of the average impedance values at each frequency and measurement zone. Liver tissue was subjected to histological examination. The minimum values of the impedance of the large omentum were recorded on day 3 after extensive liver resection. By day 14, in both zones of the large omentum, the electrical impedance increased relative to day 3 of the postoperative period and did not differ significantly from the indicators before extensive liver resection. Immediately after extensive liver resection, the bioimpedance index in all animals decreased significantly at a frequency of 2 kHz. On day 3 after surgery, the electrical impedance of the liver parenchyma at a frequency of 2 kHz increased significantly. On day 14, the electrical impedance of the liver parenchyma did not differ from the indicators before extensive resection at frequencies of 2 and 20 kHz. A strong significant correlation was found between the electrical impedance of the large omentum and liver parenchyma. At a frequency of 2 kHz, the correlation coefficient of the liver parenchyma and the proximal part of the large omentum was 0.82 and that of the distal part was 0.87 (p < 0.05). A strong correlation was detected at a frequency of 20 kHz, with r = 0.93 and 0.74, respectively, in both parts of the gland. Thus, the electrical impedance of the liver parenchyma by day 3 of the experiment increased compared with values before extensive liver resection, whereas the large omentum decreased. We believe that studying the dynamics of the electrical impedance of the large omentum after extensive liver resection is promising in the development of diagnostic criteria for the severity of liver failure.
作者简介
Sergey Leonov
О.К. Skobelkin State Scientific Center of Laser Medicine
编辑信件的主要联系方式.
Email: leonov-serg@yandex.ru
Candidate of Medical Sciences
俄罗斯联邦, MoscowDmitriy Panchenkov
Moscow State Medical and Dental University named after A.I. Evdokimov
Email: leonov-serg@yandex.ru
ORCID iD: 0000-0001-8539-4392
SPIN 代码: 4316-4651
Scopus 作者 ID: 41262312000
Doctor of Medical Sciences, Professor
俄罗斯联邦, MoscowAnton Rodin
Smolensk State Medical University
Email: doc82@yandex.ru
ORCID iD: 0000-0001-9046-7429
SPIN 代码: 3946-3240
Candidate of Medical Sciences, Associate Professor
俄罗斯联邦, Smolensk参考
- Del Basso C, Gaillard M, Lainas P, et al. Current strategies to induce liver remnant hypertrophy before major liver resection. World J Hepatol. 2021;13(11):1629–1641. doi: 10.4254/wjh.v13.i11.1629
- Liu Y, Chen Z-L, Yu X-X, Liang Y-J. Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients. Asian J Surg. 2021;44(10):1324–1325. doi: 10.1016/j.asjsur.2021.06.046
- Paquet JC, Dziri C, Hay JM, et al. Prevention of deep abdominal complications with omentoplasty on the raw surface after hepatic resection. The French Associations for Surgical Research. Am J Surg. 2000;179(2):103–109. doi: 10.1016/s0002-9610(00)00277-4
- Aono T, Sakaguchi T, Fujita N, et al. Omental delivery of prostaglandin E1 effectively increases portal venous blood flow in 66%-hepatectomized rats. Surg Today. 1997;27(5):473–476. doi: 10.1007/BF02385718
- Nekrutov AV, Karaseva OV, Roshal' LM. Greater omentum: morphofunctional characteristics and clinical significance in pediatrics. Current Pediatrics. 2007;6(6):58–63. (In Russ.).
- Khokhlov AV, Zubarev PN, Onnitsev IE. Sindrom fiksirovannogo sal'nika. Grekov's Bulletin of Surgery. 2000;159(2):71–73. (In Russ.)
- Morrison R. Remarks on some function of the omentum. Br Med J. 1906;1(2350):76–78. doi: 10.1136/bmj.1.2350.76
- Patent RUS № 2436505/20.12.2011. Byul. № 35. Leonov SD, Rodin AV. Sposob diagnostiki ostrogo vospalitel'no-destruktivnogo protsessa v bryushnoi polosti v ehksperimente. 6 p. (In Russ.).
- Panchenkov DN, Leonov SD, Rodin AV. Bioimpedance analysis in medicine. Patologicheskaya fiziologiya i ehksperimental'naya terapiya. 2014;58(2):80–86. (In Russ.).
- Patent RUS 2366360/10.09.2009. Byul. № 25. Obraztsov SA, Leonov SD, Troitskii YuV, Fedorov GN. Ustroistvo dlya izmereniya impedansa biologicheskikh tkanei. 8 p. (In Russ.).