Features of diagnostics of the peripheral lymph nodes tuberculosis
- Authors: Balasaniantc G.S.1, Dantsev V.V.1, Matinina M.S.2, Zarecky B.V.1, Muchaidze R.D.1
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Affiliations:
- Military medical academy of S.M. Kirov
- Городская туберкулезная больница № 2
- Issue: Vol 22, No 4 (2020)
- Pages: 43-46
- Section: Clinical trials
- URL: https://journals.rcsi.science/1682-7392/article/view/62803
- DOI: https://doi.org/10.17816/brmma62803
- ID: 62803
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Abstract
The analysis of the features of diagnostics of peripheral lymph nodes tuberculosis in modern conditions is carried out. For this 28 case histories of patients suffering from tuberculosis of peripheral lymph nodes were studied and 85,7% of them had a combination of tuberculosis and infection caused by the human immunodeficiency virus. All patients were undergoing biopsies or surgery of lymph nodes, and the material was examined using microbiological molecular, genetic and histological methods. 85,7% of patients had relapses with different periods of time, on average, 3–4 years, and repeated periods of tuberculosis activation. At all patients the lymph nodes were enlarged, mainly cervical (71,4%) and axillary (67,9%), the sizes of nodes varied from 1 to 5 cm, on average, 2,2±1,6 cm. In 78,6% cases tuberculosis of peripheral lymph nodes was characterized by fluctuation of nodes and the discharge of 30 to 80 ml of odorless creamy pus. It was found that tuberculosis of peripheral lymph nodes is part of a widespread tuberculous lesions especially at patients with tuberculosis associated with an infection caused by the human immunodeficiency virus. Tuberculosis of peripheral lymph nodes develops simultaneously with a specific lesion of other groups of lymph nodes – intrathoracic (75%), intra-abdominal (57,1%), which allows to generalized tuberculosis of the lymphatic system. Fibrobronchoscopy showed in 35,7% patients residual bronchial tuberculosis changes, at 14,3% – an active fistulous form of bronchial tuberculosis. Microscopy of biopsy material was negative at 78,6% of cases, while cultural examination revealed Mycobacterium tuberculosis – in 100% and molecular genetic studies – deoxyribonucleic acid of Mycobacterium tuberculosis – in 64,3% patients.
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##article.viewOnOriginalSite##About the authors
G. S. Balasaniantc
Military medical academy of S.M. Kirov
Author for correspondence.
Email: vmeda-nio@mil.ru
Russian Federation, Saint Petersburg
V. V. Dantsev
Military medical academy of S.M. Kirov
Email: vmeda-nio@mil.ru
Russian Federation, Saint Petersburg
M. S. Matinina
Городская туберкулезная больница № 2
Email: vmeda-nio@mil.ru
Russian Federation, Санкт-Петербург
B. V. Zarecky
Military medical academy of S.M. Kirov
Email: vmeda-nio@mil.ru
Russian Federation, Saint Petersburg
R. D. Muchaidze
Military medical academy of S.M. Kirov
Email: vmeda-nio@mil.ru
Russian Federation, Saint Petersburg