Intraoperative electrocorticography: variants of periodic patterns in the structural epilepsy
- Authors: Aleksandrov M.V.1,2, Kostenko I.A.1, Cherniy V.S.3, Tastanbekov M.M.1
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Affiliations:
- Polenov Neurosurgical Research Institute
- Military Medical Academy named after S.M. Kirov Ministry of Defense of the Russian Federation
- All-Russian Center for Emergency and Radiation Medicine named after A.M. Nikiforov Emercom of Russia
- Issue: Vol 23, No 4 (2021)
- Pages: 39-46
- Section: Clinical trials
- URL: https://journals.rcsi.science/1682-7392/article/view/71349
- DOI: https://doi.org/10.17816/brmma71349
- ID: 71349
Cite item
Abstract
The results of intraoperative electrocorticography for patients with the structural epilepsy are influenced by two main factors: the action of general anesthetic and the mechanisms of epileptogenesis. Under the general anesthesia, there is a dose-dependent suppression of the bioelectrical activity of the brain; you could even register the “outburst-diminution” and “outburst-suppression” types of the periodic patterns. The study was carried out to classify the variants of periodic activity registered on the intraoperative electrocorticogram for patients with a structural epilepsy. The work was carried out during the examination and surgical treatment of the two groups of patients: 1) 19 patients (men/women — 10/9, 19–45 years old) with focal drug-resistant epilepsy; 2) 19 patients (men/women — 8/11, 28–68 years old) with structural epilepsy associated with the intracerebral tumors. All patients underwent surgical removal of the epileptic focus under a neurophysiological control. Surgical interventions were performed under the sevoflurane-based inhalation anesthesia in doses from 1.0−1.5 MAC (minimum alveolar concentration). Periodic activity on intraoperative electrocorticography was represented with the “outburst-suppression” type of patterns and patterns containing epileptiform discharge graph elements: “discharge- postdischarge depression,” “outburst-suppression” with discharges against the background of depression, “small electrical elements” with epileptiform discharges. The presence of discharge graph elements in the periodic patterns has a neurophysiological correlation with a drug-resistance in the structural epilepsy.
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##article.viewOnOriginalSite##About the authors
Mikhail V. Aleksandrov
Polenov Neurosurgical Research Institute; Military Medical Academy named after S.M. Kirov Ministry of Defense of the Russian Federation
Author for correspondence.
Email: mdoktor@yandex.ru
ORCID iD: 0000-0002-9935-3249
SPIN-code: 5452-8634
doctor of medical sciences, professor
Russian Federation, Saint PetersburgIrina A. Kostenko
Polenov Neurosurgical Research Institute
Email: vdmv_irin@mail.ru
ORCID iD: 0000-0002-9527-8309
SPIN-code: 4507-5097
doctor of functional diagnostics
Russian Federation, Saint PetersburgValeriy S. Cherniy
All-Russian Center for Emergency and Radiation Medicine named after A.M. Nikiforov Emercom of Russia
Email: 9297911@list.ru
ORCID iD: 0000-0002-9791-8242
SPIN-code: 5302-7224
MD, doctor of medical sciences, professor
Russian Federation, Saint PetersburgMalik M. Tastanbekov
Polenov Neurosurgical Research Institute
Email: Tastanbekov_MM@almazovcentre.ru
ORCID iD: 0000-0003-3675-9302
SPIN-code: 1822-0196
doctor of medical sciences
Russian Federation, Saint PetersburgReferences
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