Intestinal endometriosis: features of clinical and morphological diagnostics

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

A clinical observation of the combined endometriotic lesion of the small intestine and the appendix is given below. Extragenital endometriosis is a rare pathology in which endometrioid heterotopies develop outside the reproductive system organs. At about 18–25% of women suffering from the pelvic organs endometriosis, the intestines are involved in the pathological process. In this regard, it is believed that in most cases its lesion is secondary while the primary lesion of the intestine with endometriosis is rarely observed and occurs as a result of hematogenous introduction of endometrial elements into the intestinal wall. Of all parts of the intestine, endometriosis most often affects the rectum and sigmoid colon (70−80%), then the jejunum, less often the cecum. The most rare gastrointestinal tract endometriosis localization is the appendix, the frequency of its lesion is 0.8%. It was carried out in a clinicopathologic analysis of 14 endometriosis cases in various parts of the intestine (4 cases of the small intestine lesions, 2 — rectosigmoid part of the large intestine, 2 — rectum, 2 — sigmoid colon, 3 — appendix, 1 — combined lesion of the small intestine and the appendix). In most cases, the clinical diagnosis of extragenital endometriosis is difficult, and as a rule women come with complaints typical of acute surgical pathology: intestinal obstruction, appendicitis. An important role in differential diagnosis is given to the ultrasound examination of the pelvic organs and abdominal cavity, magnetic resonance imaging, endoscopic research methods, as well as the connection of clinical symptoms with the menstrual cycle.

About the authors

Victoria A. Pechenikova

Northwest State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: p-vikka@mail.ru

PhD, MD professor

Russian Federation, Saint Petersburg

Anastasia S. Danilova

Northwest State Medical University named after I.I. Mechnikov

Email: nastenka.danilova.96@mail.ru

Resident

Russian Federation, Saint Petersburg

Victoria E. Kvarku

Northwest State Medical University named after I.I. Mechnikov

Email: viktoriya.kvarku@szgmu.ru

Doctor of ultrasound diagnostics

Russian Federation, Saint Petersburg

Nadezhda N. Ramzaeva

Northwest State Medical University named after I.I. Mechnikov

Email: dr.ramzaeva@mail.ru

Оbstetrician-gynecologist

Russian Federation, Saint Petersburg

References

  1. Adamyan LV, Zayratyants OV, Maksimova YuV, et al. Novyye patogeneticheskiye aspekty rasprostranennogo infil'trativnogo endometrioza: teorii i praktika. Problemy reproduktsii. 2010;(4):31–36. (In Russ.)
  2. Endometrioidnaya bolezn'. Ed. by Baskakovа VP, Tsvelevа YuV, Kiri YeF. Saint Petersburg: Izdatel'stvo N-L; 2002. 460 p. (In Russ.)
  3. Pechenikova VA, Kostyuchek DF. To the question of clinical characteristics of extragenital endometriosis with diverse organ localization. Vestnik Rossijskoj Voenno-medicinskoj akademii. 2010;3(31):61–66.(In Russ.)
  4. Harbitz HF. Postoperative scar endometriosis. Acta Chir. Scand. 1934;74(30):400.
  5. Cirillo F. Endometriosis of the caecum and ileo-caecal valve. A case report and review of the literature. Chir. Ital. 2008;60(4):603–606.
  6. Bessmertnaya VS, Galil-Ogly GA, Samoylov MV. Endometrioz sigmovidnoy kishki. Arkhiv patologii. 2001;67(3):43. (In Russ.)
  7. Berlanda N, Vercellini P, Fedele L. The outcomes of repeat surgery for recurrent symptomatic endometriosis. Curr. Opin. Obstet. Gynicol. 2010;22(4):320–325.
  8. Fujimoto A. Successful laporoscopic treatment of ileo–cecalendmetriosis producing bowel obstruction. J. Obstet. Gynaecol. Res. 2001;27(4):221–223.
  9. Emmanuel R, Léa M, Claude P, et al. Ileocolic intussusception due to a cecal endometriosis: case report and review of literature. Diagn. Pathol. 2012;7(1):62.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. 1.Ultrasound examination of the abdominal organs — interloop formation along the ileum

Download (249KB)
3. Fig. 2.Laparoscopy — revision of the pelvic organs and abdominal cavity

Download (340KB)
4. Fig. 3.Laparoscopy — formation of the ileum

Download (300KB)
5. Fig. 4.Endometriosis focus in the muscular layer of the wall of the small intestine. Hematoxylin-eosin stain, enl. ×180 times

Download (1MB)
6. Fig. 5.Endometriosis focus in the muscular layer of the wall of the small intestine with proliferative changes in the glands and cells epithelium of the cytogenic stroma. Hematoxylin-eosin stain, enl. ×180 time

Download (1MB)
7. Fig. 6.Endometriosis focus in the muscular layer of the wall of the small intestine with secretory changes in the glands and cells epithelium of the cytogenic stroma. Coloring hematoxylin-eosin, enl. ×240 times

Download (1MB)
8. Fig. 7.Endometriosis focus in the muscular layer of the small intestine wall with manifestations of regression. Coloring hematoxylin-eosin, enl. ×180 times

Download (2MB)
9. Fig. 8.A site of the mucous membrane of the small intestine with pronounced lymphocytic infiltration of the stroma. Coloring hematoxylin-eosin, enl. ×180 times

Download (1MB)
10. Fig. 9.The mucous membrane of the small intestine with the lymphofollicular hyperplasia symptoms. Coloring hematoxylin-eosin, enl. ×180 times

Download (1MB)

Copyright (c) 2021 Pechenikova V.A., Danilova A.S., Kvarku V.E., Ramzaeva N.N.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies