Clinical and epidemiological features of manifestations of Wolf – Parkinson – White syndrome in men of draft age with increased dysplastic stigmatization

K. S. Shulenin; Шуленин К. С.; D. V. Cherkashin; Черкашин Д. В.; G. G. Kutelev; Кутелев Г. Г.; V. A. Kachnov; Качнов В. А.; V. S. Ivanov; Иванов В. С.; R. N. Goncharuk; Гончарук Р. Н.; D. S. Bogdanov; Богданов Д. С.

doi:10.17816/brmma50523

Clinical and epidemiological features of manifestations of Wolf – Parkinson – White syndrome in men of draft age with increased dysplastic stigmatization

Authors: Shulenin K.S.¹, Cherkashin D.V.¹, Kutelev G.G.¹, Kachnov V.A.¹, Ivanov V.S.¹, Goncharuk R.N.¹, Bogdanov D.S.¹
Affiliations:
1. Military medical academy of S.M. Kirov
Issue: Vol 22, No 3 (2020)
Pages: 8-11
Section: Clinical trials
URL: https://journals.rcsi.science/1682-7392/article/view/50523
DOI: https://doi.org/10.17816/brmma50523
ID: 50523

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Abstract

Abstract. Clinical and epidemiological and electrocardiographic features of Wolf – Parkinson – White syndrome in men of military age were studied. The study was a retrospective study with a solid sample of patients. Of the 1,9056 men residents of St. Petersburg between the ages of 18 and 27, Wolf-Parkinson-White syndrome was identified in 107 (0,56%) people. The disease was asymptomatic in 38 (35,5%) patients. All identified individuals with Wolf – Parkinson – White syndrome, in addition to asthenic Constitution type, which was observed in 68,2% of cases, were assessed for signs of systemic connective tissue involvement. It was found that flat feet, scoliosis or kyphosis, myopia, as well as mitral valve prolapse and abnormally located chords in the left ventricle of the heart are detected in almost every second man of military age. Due to the inability to assess the presence of all signs of systemic connective tissue involvement, the isolation of specific variants of dysplastic phenotypes in patients with Wolf – Parkinson – White syndrome was not performed. It was found that in the presence of increased dysplastic stigmatization, the clinical course of Wolf – Parkinson – White syndrome is characterized by a lower number of asymptomatic cases (6,3 and 16,7%, respectively; p<0,05), an increase in the frequency of paroxysmal tachyarrhythmias (81,5 and 63,1%, respectively; p<0,05) and a high incidence of vegetative-vascular disorders (82,8 and 15,4%, respectively; p<0,05).

Keywords

ventricular pre-excitation, Wolf – Parkinson – White syndrome, Lown – Ganong – Levine syndrome, paroxysmal tachycardia, sudden cardiac death, connective tissue dysplasia, mitral valve prolapse, Marfan syndrome, autonomic nervous system dysfunction

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References

Бокерия, О.Л. Синдром Вольфа – Паркинсона – Уайта / О.Л. Бокерия, А.А. Ахобеков // Анналы аритмологии. – 2015. – Т. 12, № 1. – С. 235–37.
Друк, И.В. Персонифицированная оценка риска развития неблагоприятных сердечно-сосудистых осложнений у пациентов молодого возраста с дисплазией соединительной ткани / И.В. Друк [и др.] // Кардиология. – 2015. – № 3. – С. 75–84.
Качнов, В.А. Комплексный подход к профилактике внезапной сердечной смерти, разработанный в лаборатории биотехнических систем и технологий военного инновационного технополиса «ЭРА» / В.А. Качнов [и др.] // Вестн. Росс. воен.-мед. акад. – 2019. – № 3 (67). – С. 151–156.
Клинические рекомендации по проведению электро-физиологических исследований, катетерной абляции и применению имплантируемых антиаритмических устройств. – М.: ГЭОТАР-Медиа, 2017. – 701 с.
Мамчур, С.Е. Внезапная сердечная смерть и синдром Вольфа – Паркинсона – Уайта / С.Е. Мамчур, А.В. Ардашев // Клин. практика. – 2014. – № 4. – С. 60–72.
Наследственные нарушения соединительной ткани в кардиологии. Диагностика и лечение: российские рекомендации (I пересмотр) // Росс. кардиол. журн. – 2013. – Т. 99, № 1. – Прилож. 1. – С. 1–32.
Национальные рекомендации Российского научного медицинского общества терапевтов по диагностике, лечению и реабилитации пациентов с дисплазиями соединительной ткани // Мед. вестн. Сев. Кавказа. – 2016. – Т. 11, № 1. – С. 1–76.
Новикова, М.И. Особенности фенотипа и возможности обследования молодых пациентов с дисплазией соединительной ткани и аритмическим синдромом: автореф. дис. ... канд. мед. наук / М.И. Новикова. – Ставрополь, 2014. – 135 с.
Ягода, А.В. Факторы риска прогностически значимых нарушений сердечного ритма при дисплазии соединительной ткани / А.В. Ягода, М.В. Новикова, Н.Н. Гладких // Архивъ внутренней медицины. – 2015. – Т. 21, № 1. – С. 60–63.
Al-Khatib, S.M. Risk Stratification for Arrhythmic Events in Patients With Asymptomatic Pre-Excitation: A Systematic Review for the 2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: A Report of the American College of Cardiology; American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society / S.M. Al-Khatib [et al.] // J. Am. Coll. Cardiol. – 2016. – Vol. 67, № 13. – P. 1624–1638.
Bengali, R. Perioperative management of the Wolff-Parkinson-White syndrome / R. Bengali, H.J. Wellens, Y. Jiang // J. Cardiothorac. Vasc. Anesth. – 2014. – Vol. 28, № 5. – P. 1375–1386.
Cohen, M.I. PACES/HRS Expert Consensus Statement on the Management of the Asymptomatic Young Patient with a Wolff-Parkinson-White (WPW, Ventricular Preexcitation) Electrocardiographic Pattern / M.I. Cohen [et al.] // Heart Rhythm. – 2012. – Vol. 9, № 6. – P. 1006–1024.
Khairy, P. PACES/HRS Expert Consensus Statement on the Recognition and Management of Arrhythmias in Adult Congenital Heart Disease / P. Khairy [et al.] // Heart Rhythm. – 2014. – Vol. 11, № 10. – P. 102–165.
Priori, S.G. ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death / S.G. Priori [et al.] // European Heart Journal. – 2015. – Vol. 36, № 41. – P. 2793–2867.
Rao, A.L. Evaluation and Management of Wolff-Parkinson-White in Athletes / A.L. Rao [et al.] // Sports Health. – 2014. – Vol. 6, № 4. – Р. 326–332.
Svendsen, J.H. Current strategy for treatment of patients with Wolff-Parkinson-White syndrome and asymptomatic preexcitation in Europe: European Heart Rhythm Association survey / J.H. Svendsen [et al.] // Europace. – 2013. – Vol. 15, № 5. – P. 750–753.