Effect of the COVID-19 on the reproductive health indicators of cadets

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Abstract

The study investigated the influence of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 on the reproductive health indicators of cadets of military educational organizations. In the Department of Assisted Reproductive Technologies at the Clinic of Obstetrics and Gynecology of the Kirov Military Medical Academy, 183 male cadets aged 21–27 years were divided into two groups and examined. The first group consisted of 132 cadets who had mild and moderate COVID-19, and the second group included 51 cadets without COVID-19 in the anamnesis. COVID-19 was found negatively affect the reproductive health of cadets. Individuals who previously had COVID-19 were found to have a significant decrease in the level of total testosterone and decreased concentration and mobility of sperm in the ejaculate. Moreover, in cadets without COVID-19 who were vaccinated with the combined vector vaccine “Gam-COVID-Vac,” the indicators of the hormonal profile and spermograms were within the reference values. The results indicate the need for further investigation of the effect of various negative factors, including severe acute respiratory syndrome coronavirus 2, on the reproductive health of cadets of military educational organizations. Moreover, the development of preventive, therapeutic, and rehabilitation measures will reduce the risk of infertility and reproductive losses, which is consistent with the interests of national projects on healthcare and demography.

About the authors

Evgeniy V. Ivchenko

Military Medical Academy of S.M. Kirov

Email: isza@mail.ru
ORCID iD: 0000-0001-5582-1111
SPIN-code: 5228-1527

doctor of medical sciences, associate professor

Russian Federation, Saint Petersburg

Andrey A. Schmidt

Military Medical Academy of S.M. Kirov

Email: isza@mail.ru
ORCID iD: 0000-0002-9848-4714
SPIN-code: 4272-5069

candidate of medical sciences, associate professor

Russian Federation, Saint Petersburg

Dmitriу V. Ovchinnikov

Military medical academy of S.M. Kirov

Email: isza@mail.ru
ORCID iD: 0000-0001-8408-5301
SPIN-code: 5437-3457

candidate of medical sciences, associate professor

Russian Federation, Saint Petersburg

Igor S. Zakharov

Military medical academy of S.M. Kirov

Author for correspondence.
Email: isza@mail.ru
ORCID iD: 0000-0001-6167-2968
SPIN-code: 2870-2520

doctor of medical sciences, associate professor

Russian Federation, Saint Petersburg

Alexey S. Popov

Military Medical Academy of S.M. Kirov

Email: dr.a.s.popov@yandex.ru

candidate of medical sciences

Russian Federation, Saint Petersburg

Yulia L. Timoshkova

Military Medical Academy of S.M. Kirov

Email: yt6959546@yandex.ru
ORCID iD: 0000-0002-6618-3482
SPIN-code: 8175-8907

candidate of medical sciences

Russian Federation, Saint Petersburg

Said Z. Gadzhiev

Military Medical Academy of S.M. Kirov

Email: isza@mail.ru
ORCID iD: 0000-0002-4224-2441
SPIN-code: 4852-7365

clinical resident

Russian Federation, Saint Petersburg

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Supplementary files

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2. Fig. 1. Levels of total testosterone in cadets before the COVID-19 pandemic [Me, Q1÷Q3]

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3. Fig. 2. Concentrations of sperm cells in the ejaculate of cadets before the COVID-19 pandemic [Me, Q1÷Q3]

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4. Fig. 3. Motility of sperm cells in the ejaculate of cadets before the COVID-19 pandemic [Me, Q1÷Q3]

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Copyright (c) 2022 Ivchenko E.V., Schmidt A.A., Ovchinnikov D.V., Zakharov I.S., Popov A.S., Timoshkova Y.L., Gadzhiev S.Z.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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