EXPERIMENTAL JUSTIFICATION OF MODELING OF THE LIVER ABCESSES

Goal. Develop a model of purulent liver abscess (GAP), which corresponds to all the classic signs of a delimited abscess. Material and methods. Simulation of GAP was carried out in an experiment on 60 laboratory animals. Under ultrasound control (UC), a double-lumen Fogerty catheter was inserted into the established portion of the liver, a cystic cavity was formed in 3 days, which was infected and after 3 days GAP was obtained. In the modeling of GAP, clinical, planimetric, microbiological, morphological and instrumental methods of investigation were used. Results. On the third day of the experiment, a round cystic cavity of the liver with a diameter of 1,8 cm3 was formed. Three days after infection, a classic purulent abscess develops, surrounded by a dense wall formed from the liver parenchyma. As a result of the experiment, a clinical, microbiological, morphological and instrumental justification for modeling GAP with all its classic features was obtained. The conclusion. The proposed method for modeling purulent liver abscess is economically and technically profitable, minimally traumatic, provides guaranteed formation of classical GAP in the shortest possible time.

purulent liver abscess, experiment, modeling clinical, instrumental studies