Justification of tactical and technical sample requirements mass immunoprophylaxis dangerous infectious diseases in the Armed Forces of the Russian Federation

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Abstract

The results of the analysis of the current state of creating a technical means of mass immunoprophylaxis for dangerous infectious diseases are presented, including the technical level and trends in the development of developments on this problem in the Russian Federation and abroad. It was noted that in emergency situations of a biological nature, a vaccination campaign should be carried out in a short time with maximum personnel vaccination coverage, which is a massive undertaking. These requirements can be only be met with the use of mass vaccination in the form of needle-free, inhalation (aerosol) and oral vaccine administration methods. The wide use of these methods is constrained by a meager range of domestic oral vaccines, as well as the lack of technical means of mass immunization (aerosol generators, needleless injectors). This article shows that the needleless injector NI-30 (Russia) is the most appropriate for mass vaccination, in terms of technical level and operational characteristics. However, it cannot be recognized as fully meeting modern requirements due to a number of negative aspects, such as the rather large overall injector dimensions creating a large amount of obsolete structural materials. Thus, it is necessary to take into account the features of the available methods of vaccine administration when assessing the prospects for mass immunization, and it is necessary to substantiate the tactical and technical requirements for new generation samples in order to develop the technical means of mass immunization. Therefore, the development and introduction into practice of high-performance methods of mass immunization and the technical means for their implementation continues to be an urgent task.

About the authors

Oleg P. Misnokov

State Research and Testing Institute of Military Medicine

Author for correspondence.
Email: opmisnikov@mail.ru
SPIN-code: 6382-9462

Doctor of Biological Sciences, Professor
Russian Federation, Saint Petersburg

Alexander P. Savelyev

State Research and Testing Institute of Military Medicine

Email: bychkoff84@rambler.ru
SPIN-code: 2651-7480

Doctor of Medical Sciences, Professor
Russian Federation, Saint Petersburg

Alexander Stepanov

State Research and Testing Institute of Military Medicine

Email: bychkoff84@rambler.ru
ORCID iD: 0000-0002-1917-2895
SPIN-code: 7279-7055

Doctor of Medical Sciences
Russian Federation, Saint Petersburg

Andrey P. Bychkov

State Research and Testing Institute of Military Medicine

Email: bychkoff84@rambler.ru
SPIN-code: 5429-8754
Russian Federation, Saint Petersburg

Aleksandr A. Kuzin

Military Medical Academy of S.M. Kirov

Email: paster-spb@mail.ru
ORCID iD: 0000-0001-9154-7017
SPIN-code: 6220-1218

Doctor of Medical Sciences, Associate Professor
Russian Federation, Saint Petersburg

Andrey E. Zobov

Military Medical Academy of S.M. Kirov

Email: dr.andrey98@yandex.ru
ORCID iD: 0000-0001-7791-8993
SPIN-code: 4281-2680

Candidate of Medical Sciences
Russian Federation, Saint Petersburg

References

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Copyright (c) 2022 Misnokov O.P., Savelyev A.P., Stepanov A., Bychkov A.P., Kuzin A.A., Zobov A.E.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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