Prognostic assessment of risk factors for type 2 diabetes mellitus in young military personnel
- Authors: Petrankov K.V.1, Salukhov V.V.1, Pugachev M.I.1, Dobrovolskaya L.M.1, Alexandrova A.V.1, Shipilova D.A.1, Livarsky P.A.1
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Affiliations:
- Military Medical Academy of S.M. Kirov
- Issue: Vol 24, No 2 (2022)
- Pages: 277-287
- Section: Research paper
- URL: https://journals.rcsi.science/1682-7392/article/view/105334
- DOI: https://doi.org/10.17816/brmma105334
- ID: 105334
Cite item
Abstract
Risk factors for the development of type 2 diabetes mellitus were assessed in 212 military personnel aged 20–45 years serving under a contract, of which 95 people (an experienced group with risk factors) and 117 people without risk factors (an experienced group), as well as 60 practically healthy males who are not military personnel Ministry of Defense of the Russian Federation aged between 18 and 45 years (control group). It was revealed that the indicators with the greatest influence on the development of type 2 diabetes include older age, body mass index, waist circumference, insulin resistance index, and the results of the psychological questionnaire “Tendency to deviant behavior” on the scale of “Aggressiveness” as well as the questionnaire “Strong-willed self-control.” It was found, on 3-year follow-up, that prediabetes developed in 8 (8.4%) patients of the experimental group with risk factors for type 2 diabetes mellitus who did not have carbohydrate metabolism disorders, and in 8 (6.8%) patients of the experimental group. At the same time, type 2 diabetes mellitus occurred in 2 (2.5%) patients of the experimental group and in 2 (1.7%) military personnel of the experimental group with risk factors for type 2 diabetes but initially normal glycemic indices, as well as in 8 (8.4%) patients of the same group who had prediabetes at the beginning of the study. In addition, prediabetes was detected in 2 people of the control group after 3 years and type 2 diabetes mellitus in 1 person. According to the results of the study, a mathematical model is proposed to assess the likelihood of developing type 2 diabetes in military personnel with a waist circumference ≥94 cm. The proposed model has a sensitivity of 95% and a specificity of 91%. The prognostic value of a negative result is 89.2%, and that of a positive result is 87%. Thus, military personnel with a waist circumference of ≥94 cm are characterized by a more frequent development of new cases of prediabetes and type 2 diabetes mellitus than civilians, which is due to the stressful nature of military service. The use of the proposed mathematical model will make it possible to predict the development of carbohydrate metabolism disorders in military personnel with a waist circumference of ≥94 cm over a 3-year period with the identification of a risk group requiring the use of a set of preventive measures aimed at reducing body weight.
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##article.viewOnOriginalSite##About the authors
Kirill V. Petrankov
Military Medical Academy of S.M. Kirov
Author for correspondence.
Email: petrankovk@yandex.ru
ORCID iD: 0000-0001-7244-4303
SPIN-code: 7775-3011
Graduate Student
Russian Federation, Saint PetersburgVladimir V. Salukhov
Military Medical Academy of S.M. Kirov
Email: vlasaluk@yandex.ru
ORCID iD: 0000-0003-1851-0941
SPIN-code: 4531-6011
Doctor of Medical Sciences
Russian Federation, Saint PetersburgMaxim I. Pugachev
Military Medical Academy of S.M. Kirov
Email: kenig.max@mail.ru
SPIN-code: 1549-6552
Candidate of Medical Sciences
Russian Federation, Saint PetersburgLarisa M. Dobrovolskaya
Military Medical Academy of S.M. Kirov
Email: larisadobrovoskaja@mail.ru
SPIN-code: 4291-4179
Candidate of Medical Sciences
Russian Federation, Saint PetersburgAnna V. Alexandrova
Military Medical Academy of S.M. Kirov
Email: annasherrington1@gmail.com
ORCID iD: 0000-0001-8271-4186
Clinical Resident
Russian Federation, Saint PetersburgDarya A. Shipilova
Military Medical Academy of S.M. Kirov
Email: dashuta_shipilova@mail.ru
SPIN-code: 5781-6153
Candidate of Medical Sciences
Russian Federation, Saint PetersburgPavel A. Livarsky
Military Medical Academy of S.M. Kirov
Email: livarsly.98@gmail.com
SPIN-code: 1080-4234
Cadet
Russian Federation, Saint PetersburgReferences
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