下肢截肢男性体重变化
- 作者: Prilipko N.S.1, Badalov N.G.1
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隶属关系:
- Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia
- 期: 卷 24, 编号 6 (2025)
- 页面: 422-432
- 栏目: Review
- URL: https://journals.rcsi.science/1681-3456/article/view/364041
- DOI: https://doi.org/10.17816/rjpbr688722
- EDN: https://elibrary.ru/ZRWWRM
- ID: 364041
如何引用文章
详细
下肢截肢(Lower Limb Amputation, LLA)引起的体重变化与血管系统重组、运动减少、心理应激及姿–动功能障碍密切相关,对机体稳态具有显著影响。截肢后,心肺系统功能储备下降,代谢过程紊乱,运动耐受性降低。本研究分析了来自RSCI、PubMed、Embase、CINAHL、Web of Science、万方数据库、Cochrane CENTRAL和Scopus等平台的国内外文献。结果显示,随访前两年内,截肢男性的平均体重增长百分比显著高于未截肢男性。体重在第二年达到峰值,随后出现下降,但未恢复至基线水平。超过45%的经小腿截肢(Transtibial Amputation, TTA)或大腿截肢(Transfemoral Amputation, TFA)患者在第二年末体重增加超过10%,而未截肢男性为9.2%,部分足截肢(Partial Foot Amputation, PFA)患者为22.7%。至第三年,观察到体重较基线下降5%以上者比例略有增加(无截肢男性为18.5%,PFA、TTA和TFA组分别为19.7%、13.0%和22.5%)。双侧截肢者及基线体重较高者更易出现体重下降(12%,20/166,p<0.01);创伤性非爆炸伤截肢者更倾向于维持体重稳定(67%, 101/706,p=0.03);延迟性截肢者亦以体重稳定为主(79%,170/216,p<0.01)。20岁以下男性更可能出现体重增加(44%,17/39),而20岁以上者多表现为体重稳定(p=0.01)。在下肢截肢男性的体成分分析中,确认脂肪质量随截肢平面升高呈规律性增加。脂肪质量的增加主要由皮下脂肪的积累所致。代谢紊乱及心血管功能改变不利于康复,增加假肢装配与步行训练的困难,整体降低康复潜力。
作者简介
Nina S. Prilipko
Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia
编辑信件的主要联系方式.
Email: n_prilipko@mail.ru
ORCID iD: 0000-0002-1034-2640
SPIN 代码: 4540-9590
MD, Dr. Sci. (Medicine)
俄罗斯联邦, MoscowNazim G. Badalov
Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia
Email: badalovng@mrik-fmba.ru
ORCID iD: 0000-0002-1407-3038
SPIN 代码: 2264-4351
MD, Dr. Sci. (Medicine)
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