The effectiveness of UVB (311 nm emission) therapy and cyclosporine treatment in the patients with poor responsiveness to TNF-a blockers


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Abstract

The authors present data concerning the effectiveness of the application of UVB (311 nm emission) therapy and the treatment using low doses of cyclosporine in the patients receiving therapy with TNF-alpha blockers that resulted in the 50% reduction of the Psoriasis Area and Severity Index (PASI 50). The study has demonstrated that the introduction of narrow-band phototherapy into the combined treatment can make it possible to reach the PASI values of 75 and even 100%. Monitoring of the safety of the application of the combined approach has revealed the absence of early adverse reactions within 1 year after the treatment.

About the authors

Dmitry Nikolaevich Serov

State budgetary healthcare institution of Moscow "Moscow scientific-practical center of dermatovenereology and cosmetology", Moscow Healthcare Department

Email: prurigo@mail.ru
candidate med. sci., head of Department for Provision of Specialized Medical Care, Moscow Research and Practical Centre of Dermatovenerology and Cosmetology 123104, Moscow, Russian Federation

L. S Kruglova

State budgetary healthcare institution of Moscow "Moscow scientific-practical center of dermatovenereology and cosmetology", Moscow Healthcare Department

123104, Moscow, Russian Federation

E. N Ponich

Budgetary organization of Khanty-Mansi (Yugra) Autonomous District “Khanty-Mansi Clinical Dermatovenerological Dispensary”

628012, Khanty-Mansiysk, Russian Federation

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