Email this article Cutaneous toxicity of antineoplastic therapy and approaches to its correction
- Authors: Shatochina E.A.1,2, Kruglova L.S2, Kotenko K.V1
-
Affiliations:
- Federal state budgetary institution of additional professional education “Central Medical Academy”, General Management Department of RF Presidential Administration
- Moscow Research and Practical Center of Dermatovenerology and Cosmetology Moscow Health Department
- Issue: Vol 15, No 4 (2016)
- Pages: 185-187
- Section: Articles
- URL: https://journals.rcsi.science/1681-3456/article/view/41589
- DOI: https://doi.org/10.18821/1681-34562016-15-4-185-187
- ID: 41589
Cite item
Full Text
Abstract
The predictable side effects in the form of cutaneous toxicity sometimes do not allow to carry out the adequate course of antineoplastic therapy. The most frequent adverse reactions of the skin to such treatment include xerosis and pruritus. We observed 18 patients given various antineoplastic preparations who developed manifest xerosis and pruritus. The combined treatment included infrared therapy (in the frequency range of 590-620 nm) and an agent for the topical application containing 2% urea. A course of adjuvant therapy resulted in all the patients in the reduction of the severity of clinical symptoms of cutaneous toxicity of the antineoplastic preparations. In addition, certain subjective sensations (such as pruritus, skin tightness and hypersensitivity) were eliminated which significantly promoted tolerability to the course of the antineoplastic treatment. It is recommended to supplement the antineoplastic therapy by a course of phototherapy using orange light in combination with the application of a moistening agent for the external use.
Full Text
##article.viewOnOriginalSite##About the authors
Evgeniya Afanas'evna Shatochina
Federal state budgetary institution of additional professional education “Central Medical Academy”, General Management Department of RF Presidential Administration; Moscow Research and Practical Center of Dermatovenerology and Cosmetology Moscow Health Department
Email: e.a.shatokhina@gmail.com
cand. med. sci., assistant professor 121359, Moscow, Russia
L. S Kruglova
Moscow Research and Practical Center of Dermatovenerology and Cosmetology Moscow Health Department127473, Moscow, Russia
K. V Kotenko
Federal state budgetary institution of additional professional education “Central Medical Academy”, General Management Department of RF Presidential Administration121359, Moscow, Russia
References
- Lacouture M.E., Lai S.E. The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, Dryness due to EGFR inhibitors) syndrome. Br. J. Dermatol. 2006; 155 (4): 852-4.
- Марголина А.А., Эрнандес Е.И. Новая косметология. М.: ООО «Фирма «КЛАВЕЛЬ»; 2005; Т. 1.
- Круглова Л.С., Жукова О.В. Коррекция побочных эффектов противоопухолевой терапии сорафенибом. Клиническая дерматология и венерология. 2015; (3): 94-8.
- Адаскевич В.П. Кожный зуд. Дерматологический и междисциплинарный феномен. М.: Бином. Лаборатория знаний; 2014.
- Лазаренко Н.Н., Панкова И.А., Сорокина А.В. Применение фототерапии от аппаратов «Биоптрон» в дерматокосметологии: Методические рекомендации. М.; 2009.
