The application of photoinactivation of Proopiobacterium acnes by laser radiation in the violet through red wavelength range for the treatment of acne


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Abstract

The infection by Proopiobacterium acnes usually provokes the development of acne, i.e. the disease of sebaceous glands. The present study has demonstrated sensitivity of P. acnes to laser radiation in the violet (405 nm) through red (650 nm) wavelength range. The comparative in vitro investigation into the bactericidal properties of the violet and red radiation responsible for the eradication of P. acnes showed that radiation of the violet (405 nm) spectrum has a more pronounced influence on the pathogen than that of the red (650 nm) spectrum. The bactericidal effect is especially well apparent in case of the combined laser radiation in the violet through red wavelength range. Also, the in vitro experiments gave evidence that the action of laser violet radiation on P. acnes is 6 times stronger than that of red radiation; the former treatment strategy makes it possible to inactivate 95% of the colonies of this microorganism.

About the authors

Ekaterina M. Galkina

State budgetary educational institution of higher professional education “V.I. Razumovsky Saratov State Medical University”, Russian Ministry of Health

Email: kalinina13@mail.ru
Saratov

Yu. M Raigorodsky

“TRIMA” Ltd.

Saratov

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