The application of dry carbon dioxide baths and interference therapy for the treatment of various forms of stable coronary heart diseas


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Abstract

The objective of the present study was the comparative evaluation of the effectiveness of application of dry carbon dioxide baths and interference therapy for the combined treatment of the patients presenting with coronary heart disease and the early stages of atherosclerosis (the control group) or coronary syndrome X (the study group). The analysis of the results of 3234 coronary angiograms made it possible to determine the frequency of coronary syndrome X in the patients with stable coronary heart disease which proved to amount to 14.7%. It was shown that the proposed combined physico-pharmacological treatment including amlodipine therapy, dry carbon dioxide baths, and interference therapy decreases the frequency of anginal attacks and the functional class (FC) of all the patients with coronary heart disease, increases satisfaction with the results of treatment in the patients of both groups, i.e. those at the early stages of coronary artery atherosclerosis and with coronary syndrome X. Nevertheless, a more positive dynamics of the health status was documented in the patients of the study group given the combined treatment with amlodipine and the aforementioned preformed factors (p = 0.04; p = 0.0008; p = 0.00040 respectively). This observation confirms a more pronounced pathogenetic action of such treatment on the non-atherosclerotic mechanisms of the development of coronary heart disease. The patients of the two groups were not different in terms of clinical symptoms before the angiographic study was carried out while the differential pathogenetic approach based on the proposed combined physic-pharmacological treatment of the patients with ischemic heart disease and coronary syndrome X revealed their significant difference from the control patients (p = 0.05) and demonstrated well apparent positive dynamics of coronary heart disease in terms of its functional class (p = 0.08).

About the authors

E. O Penina

Odessa National Medical University

Valikhovsky pereulok 2, Odessa, Ukraine

Denis Mikhaylovich Sebov

Odessa National Medical University

Email: seboff@mail.ru
Valikhovsky pereulok 2, Odessa, Ukraine

References

  1. Kemp H.G. Left ventricular function in patients with anginal syndrome and normal coronary arteriograms. Am. J. Cardiol. 1973; 32: 375-6.
  2. Kaski J.C., Rosano G.V., Collins P. et al. Cardiac syndrome X: clinical characteristics and left ventricular function; long-term follow-up study. J. Am. Coll. Cardiol. 1995; 25: 807-14.
  3. Саnnon R.O.III, Camici P.G., Epstein S.E. Pathophysiological dilemma of syndrome X. Circulation. 1992; 85: 883-92.
  4. Thygesen K., Alpert J.S., Jaffe A.S. et al. EXPERT CONSENSUS DOCUMENT. Third universal definition of myocardial infarction. Eur. Heart J. 2012; 33: 2551-67. doi: 10.1093/eurheartj/ehs184
  5. Spertus J.A., Winder J.A., Dewhurst T.A. et al. Development and evaluation of the Seatle Angina Questionnaire: A new functional status measure for coronary artery disease. J. Am. Coll. Cardiol. 1995; 25: 333-41.

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