THE RESULTS OF THE COMBINED PHYSIOTHERAPEUTIC TREATMENT OF THE PATIENTS PRESENTING WITH GLAUCOMA

A scientifically-substantiated rationale is provided for the combined application of ultrasound therapy and endonasal electrophoresis of the neuropeptide preparation cortexin for the treatment of the patients presenting with open-angle glaucoma (OAG). A total of 121 patients with stage I-III OAG and normalized intraocular pressure were available for the observation. They were allocated to 4 groups regardless of the therapeutic modality chosen for the treatment. The patients of the main study group underwent continuous (without breaks) ultrasonic irradiation of the eyeball plus endonasal cortexin electrophoresis. In the first reference group only endonasal cortexin electrophoresis was applied, the patients of the second reference group were given intramuscular injections of cortexin, those of the control group received standard therapy with neuro- and angioprotectors. This basal therapy was also provided to the patients of all the rest groups. Positive dynamics of clinical, functional, perimetric, and electrophysiological characteristics was documented in the main study group and in the reference groups. The beneficial effects of continuous ultrasonic irradiation combined with endonasal cortexin electrophoresis were more pronounced that those of other therapeutic modalities both in the immediate post-treatment period and during the long-term follow-up.

primary open-angle glaucoma, ultrasound therapy, neuroprotectors, endonasal electrophoresis