Мақаланы E-mail арқылы жіберу Exogenous heat shock protein HSP70 reduces response of human neuroblastoma cells to lipopolysaccharide
- Авторлар: Yurinskaya M.M.1,2, Funikov S.Y.2, Evgen’ev M.B.1,2, Vinokurov M.G.1
-
Мекемелер:
- Institute of Cell Biophysics
- Engelhardt Institute of Molecular Biology
- Шығарылым: Том 469, № 1 (2016)
- Беттер: 239-243
- Бөлім: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/211371
- DOI: https://doi.org/10.1134/S1607672916040025
- ID: 211371
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
The effect of exogenous heat shock protein HSP70 and lipopolysaccharide (LPS) on the production of reactive oxygen species (ROS), TNFα secretion, and mRNA expression by human neuroblastoma SK-N-SH cells. It was shown that exogenous HSP70 protects neuroblastoma cells from the action of LPS. The protection mechanism of HSP70 includes a reduction in the production of ROS and TNFα and a decrease in the expression of TLR4 and IL-1β mRNA in SK-N-SH cells induced by LPS.
Авторлар туралы
M. Yurinskaya
Institute of Cell Biophysics; Engelhardt Institute of Molecular Biology
Email: mg-vinokurov@mail.ru
Ресей, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290; ul. Vavilova 32, Moscow, 119991
S. Funikov
Engelhardt Institute of Molecular Biology
Email: mg-vinokurov@mail.ru
Ресей, ul. Vavilova 32, Moscow, 119991
M. Evgen’ev
Institute of Cell Biophysics; Engelhardt Institute of Molecular Biology
Email: mg-vinokurov@mail.ru
Ресей, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290; ul. Vavilova 32, Moscow, 119991
M. Vinokurov
Institute of Cell Biophysics
Хат алмасуға жауапты Автор.
Email: mg-vinokurov@mail.ru
Ресей, ul. Institutskaya 3, Pushchino, Moscow oblast, 142290
Қосымша файлдар
