Genomic and proteomic profiles of Acholeplasma laidlawii strains differing in sensitivity to ciprofloxacin


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As a result of comparative analysis of complete genomes as well as cell and vesicular proteomes of A. laidlawii strains differing in sensitivity to ciprofloxacin, it was first shown that the mycoplasma resistance to the antibiotic is associated with the reorganization of genomic and proteomic profiles, which concerns many genes and proteins involved in fundamental cellular processes and realization of bacterial virulence.

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E. Medvedeva

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

编辑信件的主要联系方式.
Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008

M. Davydova

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111

A. Mouzykantov

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008

N. Baranova

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008

T. Grigoreva

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111

M. Siniagina

Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Kremlevskaya 18, Kazan Tatarstan, 420008

E. Boulygina

Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Kremlevskaya 18, Kazan Tatarstan, 420008

O. Chernova

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008

V. Chernov

Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center; Kazan (Volga Region) Federal University

Email: elena-med@list.ru
俄罗斯联邦, ul. Lobachevskogo 2/31, Kazan Tatarstan, 420111; ul. Kremlevskaya 18, Kazan Tatarstan, 420008

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