Innate Immune Protein Tag7 Stimulates the Appearance of Cytotoxic NK Cells after Incubation with Lymphocytes
- Autores: Sharapova T.N.1, Romanova E.A.1, Sashchenko L.P.1, Gnuchev N.V.1, Yashin D.V.1
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Afiliações:
- Institute of Gene Biology, Russian Academy of Sciences
- Edição: Volume 484, Nº 1 (2019)
- Páginas: 92-94
- Seção: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212860
- DOI: https://doi.org/10.1134/S1607672919010253
- ID: 212860
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Resumo
Tag7 (PGRP-S) is an innate immune protein that is involved in the antibacterial and antitumor defense and stimulates the maturation of cytotoxic lymphocyte subpopulations. It was found that the incubation of lymphocytes with Tag7 for 3 days promotes the appearance of cytotoxic NK cells that are active against a number of tumor cell lines.
Sobre autores
T. Sharapova
Institute of Gene Biology, Russian Academy of Sciences
Autor responsável pela correspondência
Email: sharapovatat.nik@gmail.com
Rússia, Moscow, 119334
E. Romanova
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Rússia, Moscow, 119334
L. Sashchenko
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Rússia, Moscow, 119334
N. Gnuchev
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Rússia, Moscow, 119334
D. Yashin
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Rússia, Moscow, 119334
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