Innate Immune Protein Tag7 Stimulates the Appearance of Cytotoxic NK Cells after Incubation with Lymphocytes
- Авторы: Sharapova T.N.1, Romanova E.A.1, Sashchenko L.P.1, Gnuchev N.V.1, Yashin D.V.1
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Учреждения:
- Institute of Gene Biology, Russian Academy of Sciences
- Выпуск: Том 484, № 1 (2019)
- Страницы: 92-94
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212860
- DOI: https://doi.org/10.1134/S1607672919010253
- ID: 212860
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Аннотация
Tag7 (PGRP-S) is an innate immune protein that is involved in the antibacterial and antitumor defense and stimulates the maturation of cytotoxic lymphocyte subpopulations. It was found that the incubation of lymphocytes with Tag7 for 3 days promotes the appearance of cytotoxic NK cells that are active against a number of tumor cell lines.
Об авторах
T. Sharapova
Institute of Gene Biology, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: sharapovatat.nik@gmail.com
Россия, Moscow, 119334
E. Romanova
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Россия, Moscow, 119334
L. Sashchenko
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Россия, Moscow, 119334
N. Gnuchev
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Россия, Moscow, 119334
D. Yashin
Institute of Gene Biology, Russian Academy of Sciences
Email: sharapovatat.nik@gmail.com
Россия, Moscow, 119334
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