Innate Immune Protein Tag7 Stimulates the Appearance of Cytotoxic NK Cells after Incubation with Lymphocytes

T. N. Sharapova; E. A. Romanova; L. P. Sashchenko; N. V. Gnuchev; D. V. Yashin

doi:10.1134/S1607672919010253

Innate Immune Protein Tag7 Stimulates the Appearance of Cytotoxic NK Cells after Incubation with Lymphocytes

作者: Sharapova T.N.¹, Romanova E.A.¹, Sashchenko L.P.¹, Gnuchev N.V.¹, Yashin D.V.¹
隶属关系:
1. Institute of Gene Biology, Russian Academy of Sciences
期: 卷 484, 编号 1 (2019)
页面: 92-94
栏目: Biochemistry, Biophysics, and Molecular Biology
URL: https://journals.rcsi.science/1607-6729/article/view/212860
DOI: https://doi.org/10.1134/S1607672919010253
ID: 212860

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详细

Tag7 (PGRP-S) is an innate immune protein that is involved in the antibacterial and antitumor defense and stimulates the maturation of cytotoxic lymphocyte subpopulations. It was found that the incubation of lymphocytes with Tag7 for 3 days promotes the appearance of cytotoxic NK cells that are active against a number of tumor cell lines.