MicroRNA in hormonal mechanisms of regulation of NK cell function


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Resumo

We investigated the effect of human chorionic gonadotropin, estriol, leptin, ghrelin, and kisspeptin on the microRNA expression in separated NK cells. All of these hormones are able to effectively modulate the expression of microRNAs both stimulating and suppressing the cytotoxic potential of NK cells and thereby indirectly regulate the functions of these lymphocytes.

Sobre autores

S. Shirshev

Institute of Ecology and Genetics of Microorganisms, Ural Department

Email: nirina5@mail.ru
Rússia, Perm, 614081

I. Nekrasova

Institute of Ecology and Genetics of Microorganisms, Ural Department

Autor responsável pela correspondência
Email: nirina5@mail.ru
Rússia, Perm, 614081

O. Gorbunova

Institute of Ecology and Genetics of Microorganisms, Ural Department

Email: nirina5@mail.ru
Rússia, Perm, 614081

E. Orlova

Institute of Ecology and Genetics of Microorganisms, Ural Department

Email: nirina5@mail.ru
Rússia, Perm, 614081

I. Maslennikova

Institute of Ecology and Genetics of Microorganisms, Ural Department

Email: nirina5@mail.ru
Rússia, Perm, 614081

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