The level of cytokines and expression of caspase genes in rheumatoid arthritis


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

The level of TNFα and IL6 in the blood plasma of patients with rheumatoid arthritis (RA) who received antiinflammatory therapy with methotrexate (MT) was significantly lower than in the patients without MT treatment. The level of caspase 6 and 9 gene transcripts in peripheral blood lymphocytes in patients with rheumatoid arthritic diagnosed for the first time and in patients with MT treatment were not significantly different. At the same time, the level of caspase 3 mRNA expression was significantly higher in the cells of the RA patients with MT therapy compared to the patients without MT therapy.

Авторлар туралы

I. Malysheva

Institute of Biology, Karelian Research Center

Хат алмасуға жауапты Автор.
Email: i.e.malysheva@yandex.ru
Ресей, ul. Pushkinskaya 11, Petrozavodsk, 185910

L. Topchieva

Institute of Biology, Karelian Research Center

Email: i.e.malysheva@yandex.ru
Ресей, ul. Pushkinskaya 11, Petrozavodsk, 185910

O. Barysheva

Petrozavodsk State University

Email: i.e.malysheva@yandex.ru
Ресей, pr. Lenina 33, Petrozavodsk, Karelia, 185910

I. Kurbatova

Institute of Biology, Karelian Research Center

Email: i.e.malysheva@yandex.ru
Ресей, ul. Pushkinskaya 11, Petrozavodsk, 185910

O. Vasykova

Petrozavodsk State University

Email: i.e.malysheva@yandex.ru
Ресей, pr. Lenina 33, Petrozavodsk, Karelia, 185910

N. Vezikova

Petrozavodsk State University

Email: i.e.malysheva@yandex.ru
Ресей, pr. Lenina 33, Petrozavodsk, Karelia, 185910

I. Marusenko

Petrozavodsk State University

Email: i.e.malysheva@yandex.ru
Ресей, pr. Lenina 33, Petrozavodsk, Karelia, 185910

N. Nemova

Institute of Biology, Karelian Research Center

Email: i.e.malysheva@yandex.ru
Ресей, ul. Pushkinskaya 11, Petrozavodsk, 185910

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

© Pleiades Publishing, Ltd., 2016