Antitumor effect of arabinogalactan and platinum complex


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The article presents the results of investigation of antitumor properties of platinum–arabinogalactan complex. We showed the ability of the complex to inhibit the growth of Ehrlich ascites tumor cells. It is found that the distribution of the platinum–arabinogalactan complex is not specific only for tumor cells in mice. The complex was found in all tissues and organs examined (ascites cells, embryonic cells, kidney, and liver). The mechanism of action of the arabinogalactan–platinum complex may be similar to cisplatin as the complex is able to accumulate in tumor cells.

作者简介

A. Starkov

Institute of Chemistry and Chemical Technology, Siberian Branch

Email: tzamay@yandex.ru
俄罗斯联邦, Krasnoyarsk

T. Zamay

Voino-Yasenetskii State Medical University; Siberian Federal University; Kirenskii Institute of Physics, Siberian Branch

编辑信件的主要联系方式.
Email: tzamay@yandex.ru
俄罗斯联邦, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk krai, 660022; Svobodnyi pr. 79, Krasnoyarsk, 660041; Krasnoyarsk, 660036

A. Savchenko

Voino-Yasenetskii State Medical University; Siberian Federal University

Email: tzamay@yandex.ru
俄罗斯联邦, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk krai, 660022; Svobodnyi pr. 79, Krasnoyarsk, 660041

E. Ingevatkin

Voino-Yasenetskii State Medical University

Email: tzamay@yandex.ru
俄罗斯联邦, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk krai, 660022

N. Titova

Siberian Federal University

Email: tzamay@yandex.ru
俄罗斯联邦, Svobodnyi pr. 79, Krasnoyarsk, 660041

O. Kolovskaya

Voino-Yasenetskii State Medical University; Kirenskii Institute of Physics, Siberian Branch

Email: tzamay@yandex.ru
俄罗斯联邦, ul. Partizana Zheleznyaka 1, Krasnoyarsk, Krasnoyarsk krai, 660022; Krasnoyarsk, 660036

N. Luzan

Siberian Federal University

Email: tzamay@yandex.ru
俄罗斯联邦, Svobodnyi pr. 79, Krasnoyarsk, 660041

P. Silkin

Siberian Federal University

Email: tzamay@yandex.ru
俄罗斯联邦, Svobodnyi pr. 79, Krasnoyarsk, 660041

S. Kuznetsova

Institute of Chemistry and Chemical Technology, Siberian Branch; Siberian Federal University

Email: tzamay@yandex.ru
俄罗斯联邦, Krasnoyarsk; Svobodnyi pr. 79, Krasnoyarsk, 660041

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