Analysis of ERK1/2 kinases in the inferior colliculus of rats genetically prone to audiogenic seizures during postnatal development
- 作者: Chernigovskaya E.V.1, Lebedenko O.O.1, Nidenfyur A.V.1, Nikitina L.S.1, Glazova M.V.1
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隶属关系:
- Sechenov Institute of Evolutionary Physiology and Biochemistry
- 期: 卷 476, 编号 1 (2017)
- 页面: 296-298
- 栏目: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/211966
- DOI: https://doi.org/10.1134/S1607672917050015
- ID: 211966
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详细
The activity of ERK1/2 kinases in the quadrigemina inferior colliculus of Krushinsky–Molodkina rats of different age, which are characterized by an increased seizure readiness compared to Wistar rats, was analyzed. An increased (probably genetically determined) activity of these enzymes during the development of epileptiform activity in ontogeny was found, which may be the cause of abnormalities in the neurotransmitter system functioning.
作者简介
E. Chernigovskaya
Sechenov Institute of Evolutionary Physiology and Biochemistry
编辑信件的主要联系方式.
Email: chern755@mail.ru
俄罗斯联邦, St. Petersburg, 194223
O. Lebedenko
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: chern755@mail.ru
俄罗斯联邦, St. Petersburg, 194223
A. Nidenfyur
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: chern755@mail.ru
俄罗斯联邦, St. Petersburg, 194223
L. Nikitina
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: chern755@mail.ru
俄罗斯联邦, St. Petersburg, 194223
M. Glazova
Sechenov Institute of Evolutionary Physiology and Biochemistry
Email: chern755@mail.ru
俄罗斯联邦, St. Petersburg, 194223
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