Correlation between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer


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The mRNA content of the transcription factors KLF5 and ZEB1 was studied in pancreatic tumor tissues and in fetal and normal pancreas. Transcription of these factors was not high and similar in normal and fetal pancreatic tissues but greatly increased in the pancreatic ductal adenocarcinoma tissues. A significant positive correlation between the KLF5 and ZEB1 transcription levels in the pancreatic tumor tissues was observed.

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M. Zinovyeva

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

编辑信件的主要联系方式.
Email: mzinov@mail.ru
俄罗斯联邦, Moscow, 117997

L. Nikolaev

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

Email: mzinov@mail.ru
俄罗斯联邦, Moscow, 117997

L. Kondratyeva

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

Email: mzinov@mail.ru
俄罗斯联邦, Moscow, 117997

T. Vinogradova

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

Email: mzinov@mail.ru
俄罗斯联邦, Moscow, 117997

E. Sverdlov

Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

Email: mzinov@mail.ru
俄罗斯联邦, Moscow, 117997

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